Aim: To study the influence of season on patch tests results.
Methods: We conducted a retrospective epidemiological study which concerned all the patients of the Tunisian center, who consulted in the Dermato-Allergology Unit of Occupational Medicine Department of Farhat Hached University Hospital-Sousse (Tunisia) over a period of 07 years. All the patients were tested by the European Standard Battery allergens (BSE).
Results: The data of 1000 patch tests were analyzed during the study period. More than half of the patch tests (58.6%) was positive. In winter, 63% of patch tests showed a positive reaction versus 52% of patch tests in summer without a statistically significant association. However, results of lanolin alcohols, epoxy resin, and Sesquiterpene lactone mix varied significantly with season. Atopy was significantly associated with 18.8% of positive reactions in winter and only with 5.2% of positive reactions in summer ( = 0.015).
Conclusion: Seasonal variations in patch tests results were more significant with some allergens of European Standard Battery and in atopic patients.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683155 | PMC |
| http://dx.doi.org/10.1155/2020/8316753 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Prevalence and factors associated with sensitivity to methylisothiazolinone in individuals with suspected allergic contact dermatitis: A cross-sectional study.
Rev Alerg Mex
December 2024
Escola Superior de Ciências da Saúde ESCS Brasília/DF Brazil, Allergy and Dermatology Outpatient Unit at the Hospital Regional da Asa Norte HRAN - SMHN Q 2.
Objectives: To evaluate the prevalence of methylisothiazolinone sensitivity and associated factors in individuals with suspected allergic contact dermatitis.
Methods: Cross-sectional study based on patch tests, including methylisothiazolinone 0.2%, in 286 participants with suspected allergic contact dermatitis, in Brasília/DF, Brazil, between March/2020 and March/2022.
Basic Science and Pathogenesis.
Alzheimers Dement
December 2024
University of Arizona, Tucson, AZ, USA.
Background: Cerebral microvascular dysfunction and nitro-oxidative stress are present in patients with Alzheimer's disease (AD) and may contribute to disease progression and severity. A pro-nitro-oxidative environment can lead to post-translational modifications of ion channels central to microvascular regulation in the brain, including the large conductance Ca-activated K channels (BK). Nitro-oxidative modulation of BK can resulting in decreased activity and vascular hyper-contractility, thus compromising neurovascular regulation.
View Article and Find Full Text PDFBasic Science and Pathogenesis.
Alzheimers Dement
December 2024
First Affiliated Hospital, Zhejiang University, Hangzhou, Zhejiang, China.
Background: Synaptic plasticity impairment plays a critical role in the pathogenesis of Alzheimer's disease (AD), Smad4, a central intracellular signal transmission mediator of transmission of transforming growth factor-β (TGF-β) signaling, plays a pivotal role in many biological processes, including cell differentiation, migration, apoptosis and tumorigenesis. Emerging evidence has demonstrated that Smad4 is also involved in the pathogenesis of AD. Once TGF-β signaling is stimulated, Smad4 interaction with Sp1 and Smad3 induces the transcriptional activation of APP.
View Article and Find Full Text PDF[Contact dermatitis in children].
Ugeskr Laeger
December 2024
Hudafdeling I og Allergicentret, Odense Universitetshospital.
Contact dermatitis is a common skin condition in children caused by environmental exposure to irritants or allergens. Manifestation of common endogenous eczemas, e.g.
View Article and Find Full Text PDFSlick potassium channels limit TRPM3-mediated activation of sensory neurons.
Front Pharmacol
December 2024
Institute of Pharmacology and Clinical Pharmacy, Goethe University Frankfurt, Frankfurt, Germany.
Article Synopsis
- Specialized heat-sensitive neurons in the skin relay heat sensations, with the sodium-activated potassium channel Slick playing a significant role in controlling noxious heat responses.
- Researchers created mice lacking Slick in specific sensory neurons (SNS-Slick mice) and found these mice had quicker responses to painful heat tests compared to normal mice.
- Further experiments revealed that Slick works alongside the heat sensor TRPM3, suggesting that Slick helps to inhibit pain responses by modulating TRPM3 activity in sensory neurons.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!