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Draft Genome Sequences of Lysostaphin-Resistant (K07-204) and Lysostaphin-Susceptible (K07-561) Staphylococcus aureus Sequence Type 72 Strains Isolated from Patients in South Korea. | LitMetric

AI Article Synopsis

  • - Methicillin-resistant sequence type 72 (ST72) is common in South Korea and is resistant to various antibiotics.
  • - ST72 strains show varying degrees of resistance to a specific antibiotic called lysostaphin.
  • - Researchers used draft genome sequencing and subtractive genomics to investigate how ST72 isolates develop resistance to lysostaphin.

Article Abstract

Methicillin-resistant sequence type 72 (ST72) is prevalent in South Korea and has shown resistance to multiple antimicrobials. ST72 isolates display different levels of resistance to the antistaphylococcal lysostaphin. Draft genome sequencing of ST72 human isolates exhibiting lysostaphin resistance or susceptibility was performed to better understand the mechanism of lysostaphin resistance using subtractive genomics.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7714846PMC
http://dx.doi.org/10.1128/MRA.01057-20DOI Listing

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