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Dynamic changes in medication burden leading to fall and hospital readmissions in older adults: Toward a strategy for improving risk and managing costs.
J Manag Care Spec Pharm
January 2025
Department of Internal Medicine, UT Health McGovern Medical School, Houston, TX.
The majority of a health plan's performance and designated Star Rating is related to medication-related behavior, eg, medication adherence, medication review, and reconciliation, that are intricately related to adverse drug events (ADEs). Altered pharmacodynamics and pharmacokinetics owing to aging make older adults more vulnerable to ADEs like falls, fractures, hospitalizations, and mortality. Prevention of avoidable risk factors such as medication burden can help maintain quality of life.
View Article and Find Full Text PDFPharmacy Integrated Transitions (PIT) trial: a protocol for a pragmatic cluster-randomised crossover trial.
BMJ Open
December 2024
Health Services, University of Washington, Seattle, Washington, USA.
Introduction: Ineffective coordination during care transitions from hospitals to skilled nursing facilities (SNFs) costs Medicare US$2.8-US$3.4 billion annually and results in avoidable adverse events.
View Article and Find Full Text PDFQuality and Safety Indicators for Care Transitions by Older Adults: A Scoping Review.
J Am Med Dir Assoc
December 2024
Registry of Senior Australians (ROSA) Research Centre, Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Bedford Park, South Australia, Australia; Registry of Senior Australians (ROSA) Research Centre, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia; UniSA Allied Health and Human Performance, University of South Australia, Adelaide, South Australia, Australia; Adelaide Medical School, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.
Objective: To identify quality and safety indicators routinely used to monitor, evaluate, and improve care transitions for older adults globally.
Design: A scoping literature review.
Setting And Participants: This review identified indicators used internationally to monitor and evaluate the quality and safety of care transitions by older adults.
Prediction of Medication-Related Osteonecrosis of the Jaw in Patients Receiving Antiresorptive Therapy Using Machine Learning Models.
J Oral Maxillofac Surg
December 2024
Assistant Professor, Research and Data Development, The Securities and Exchange Commission, Bangkok, Thailand.
Background: Medication-related osteonecrosis of the jaw (MRONJ) is a serious complication associated with the use of antiresorptive agents, impacting patient quality of life and treatment outcomes. Predictive modeling may aid in a better understanding of MRONJ development.
Purpose: The study aimed to evaluate machine learning (ML)-based models for predicting MRONJ in patients receiving antiresorptive therapy.
Impact of pharmacist-led discharge medication reconciliation on error and patient harm prevention at a large academic medical center.
J Am Coll Clin Pharm
August 2024
Clinical and Translational Science Center, University of California, Davis Health, Sacramento, California, USA.
Introduction: Medication errors during hospital discharge can lead to adverse outcomes, medication-related readmissions, and increased health care costs. Pharmacist-led medication reconciliation at discharge is a potential solution to mitigate poor outcomes and optimize medication safety.
Objectives: This study aimed to quantify medication errors identified at discharge and characterize the severity of patient harm prevented following pharmacist-led discharge medication reconciliation.
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