Endosomal recycling reconciles the Alzheimer's disease paradox.

Sci Transl Med

Ann Romney Center for Neurologic Diseases, Department of Neurology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.

Published: December 2020

A hub-and-spoke model with endosomal recycling as the hub can reconcile the pathogenic contribution of amyloid precursor protein to Alzheimer's disease.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8025181PMC
http://dx.doi.org/10.1126/scitranslmed.abb1717DOI Listing

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