The effects of variable thermal conductivity on heat transfer and entropy generation in a flow over a curved surface are investigated in the present study. In addition, the effects of energy dissipation and Ohmic heating are also incorporated in the modelling of the energy equation. Appropriate transformations are used to develop the self-similar equations from the governing equations of momentum and energy. The resulting self-similar equations are then solved by the Generalized Differential Quadrature Method (GDQM). For the validation and precision of the developed numerical solution, the resulting equations are also solved numerically using the Runge-Kutta-Fehlberg method (RKFM). An excellent agreement is found between the numerical results of the two methods. To examine the impacts of emerging physical parameters on velocity, temperature distribution and entropy generation, the numerical results are plotted against the various values of physical flow parameters and discussed physically in detail.
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http://dx.doi.org/10.3390/e20120943 | DOI Listing |
AAPS PharmSciTech
January 2025
School of Chinese Materia Medica, Beijing University of Chinese Medicine, Beijing, 102488, China.
Paeoniflorin is a natural pharmaceutical ingredient with a widely biological activity. However, as a hydrophilic drug, the problem of low transdermal rate limits its clinical application. To overcome this shortage, LUVs were used as biocompatible carriers of paeoniflorin in this study.
View Article and Find Full Text PDFJ Biomech Eng
January 2025
Department of Mechanical Engineering Marshall University, Huntington, WV 25755, USA; Department of Biomedical Engineering Marshall University, Huntington, WV 25755, USA.
Cell-laden, scaffold-based tissue engineering methods have been successfully utilized for the treatment of bone fractures. In such methods, the rate of scaffold biodegradation, transport of nutrients, and removal of cell metabolic wastes are critical fluid-dynamics factors, affecting tissue regeneration. Therefore, there is a critical need to identify the underlying material transport mechanisms associated with stem cell-driven, scaffold-based bone tissue regeneration.
View Article and Find Full Text PDFAdv Mater
January 2025
Department of Mechanical and Aerospace Engineering, Cornell University, 124 Hoy Road, Ithaca, NY, 14850, USA.
The adaptable, modular structure of muscles, combined with their confluent energy storage allows for numerous architectures found in nature: trunks, tongues, and tentacles to name some more complex ones. To provide an artificial analog to this biological soft muscle, a self-powered, soft hydrostat actuator is presented. As an example of how to use these modules, a worm robot is assembled where the near totality of the body stores electrochemical potential.
View Article and Find Full Text PDFSci Rep
December 2024
Jiangsu Key Laboratory of Oil-Gas Storage and Transportation Technology, Changzhou University, Changzhou, 213164, Jiangsu, China.
Bend pipe is a common part of long distance pipeline. There is very important to study the flow law of hydrate particles in the bend pipe, and pipeline design will be optimized. In addition, the efficiency and safety of pipeline gas transmission will be improved.
View Article and Find Full Text PDFInt J Pharm
December 2024
SkinAxis LLC, Cedar Knolls, NJ, USA. Electronic address:
In this study we evaluated the effects of flow lamination on aerosol flow dynamics and deposition at the exit point in testing models with spatial barriers (narrowing or curving).We compared ModiFlow (MF) to an idealized Standard Spacer (SS) in their efficiency of delivery of aerosolized medication (fluticasone) across different types of spatial barriers. Fluticasone propionate HFA Inhaler from Prasco Labs 220 µg per actuation was used to deliver 1 spray in each test tube.
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