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Complications After Dental Sedation: A Myotonic Mystery Case Report.
Anesth Prog
December 2022
Associate Professor and Hospital Attending, The Ohio State University College of Dentistry General Practice Residency Program and Wexner Medical Center, Columbus, Ohio.
Myotonic dystrophy (dystrophia myotonica; DM) is an uncommon progressive hereditary muscle disorder that can present with variable severity at birth, in early childhood, or most commonly as an adult. Patients with DM, especially type 1 (DM1), are extremely sensitive to the respiratory depressant effects of sedative-hypnotics, anxiolytics, and opioid agonists. This case report describes a 37-year-old male patient with previously undiagnosed DM1 who received dental care under minimal sedation using intravenous midazolam.
View Article and Find Full Text PDFImproved Tumor Control Related to Radiotherapy Technological Development for Hypopharyngeal Cancer.
Laryngoscope
February 2021
Department of Radiation Oncology, University of California San Francisco, San Francisco, California.
Objectives/hypothesis: Squamous cell carcinoma of the hypopharynx (SCCHP) is associated with worse survival compared to other head and neck subsites. This report quantifies the impact of technological improvements in radiotherapy (RT) on outcomes over 6 decades.
Methods: Patients with SCCHP receiving curative-intent treatment between 1962 and 2015 were retrospectively reviewed.
Management of Chordoma and Chondrosarcoma with Fractionated Stereotactic Radiotherapy.
Front Surg
June 2017
Department of Radiation Oncology, University of California San Francisco, San Francisco, CA, United States.
Objective: To evaluate the efficacy and toxicity of fractionated stereotactic radiotherapy (FSRT) for chordoma and chondrosarcoma.
Methods: Twenty consecutive patients with a histopathologic diagnosis of chordoma ( = 16) or chondrosarcoma ( = 4) treated between 2010 and 2016 were retrospectively identified. All patients underwent FSRT in five fractions to a median dose of 37.
Receiver operating curves and dose-volume analysis of late toxicity with stereotactic body radiation therapy for prostate cancer.
Pract Radiat Oncol
March 2017
Department of Radiation Oncology, Oakland University William Beaumont School of Medicine, Beaumont Health System, Royal Oak, Michigan. Electronic address:
Purpose: The purpose of this study was to evaluate a receiver operating characteristic (ROC) curve method to determine dose thresholds with late genitourinary (GU) toxicity after stereotactic body radiation therapy for prostate cancer.
Methods And Materials: Seventy-eight patients diagnosed with low- to intermediate-risk prostate cancer and treated with stereotactic body radiation therapy alone were reviewed retrospectively. All patients received a total dose of 38 Gy in 4 fractions with a planning target volume expansion of 2 mm.
Sentinel Lymph Node Mapping in Post-Mastectomy Chest Wall Recurrences: Influence on Radiation Treatment Fields and Outcome.
Ann Surg Oncol
March 2016
Department of Radiation Oncology, University of California, San Francisco, San Francisco, CA, USA.
Background And Objectives: Invasive chest wall recurrences (CWR) following mastectomy are typically treated with surgical excision, radiation therapy (RT) to the chest wall and supraclavicular (SCV) region, and appropriate systemic therapy. Repeat axillary surgery is not routinely performed if the axilla is clinically negative. We evaluated sentinel node biopsy (SNB) in patients with an isolated invasive CWR, for identification and biopsy rates, non-axillary drainage, and clinical implications for radiation fields and outcome.
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