A large field-of-view high-resolution hard x-ray microscope using polymer optics.

We present an effective approach using a matched pair of polymer-based condenser-objective lenses to build a compact full-field x-ray microscope with a high spatial resolution. A unique condenser comprising arrays of high-aspect-ratio prisms with equilateral cross section is used for uniformly illuminating samples over a large field of view (FOV) from all angles, which match the acceptance of an objective made of interdigitated orthogonal rows of one-dimensional lenses. State-of-the-art Talbot grating interferometry used to characterize these lenses for the first time revealed excellent focusing properties and minimal wavefront distortions. Using a specific lens pair designed for 20 keV x rays, short-exposure times, and image registration with a cross-correlation technique, we circumvent vibrational instabilities to obtain distortion-free images with a uniform resolution of 240 nm (smallest resolvable line pair) over a large FOV, 80 × 80 µm in extent. The results were contrasted with those collected using commercial two-dimensional parabolic lenses with a smaller FOV. This approach implemented on a diffractometer would enable diffraction-contrast or dark-field microscopy for fast observations of "mesoscopic" phenomena in real space complementing reciprocal-space studies using diffraction on the same instrument.