Urinary tract infections (UTIs) are considered to be the most common infections worldwide, having an incidence rate of 40-60% in women. Moreover, the prevalence of this disorder in adult women is 30 times more than in men. UTIs are usually found in many hospitals and clinical practice; as disorders, they are complicated and uncomplicated; in uncomplicated cases, there is no structural or functional abnormality in the urogenital tract. However, obstruction, retention of urine flow and use of catheters increase the complexity. There are several bacteria (e.g., , , , etc.) successfully residing in the tract. The diagnosis must not only be accurate but rapid, so early detection is an important step in the control of UTIs caused by uropathogens. The treatment of UTIs includes appropriate antimicrobial therapy to control the infection and kill the causal microbes inside the body. A long-time usage of antibiotics has resulted in multidrug resistance causing an impediment in treatment. Thus, alternative, combinatorial medication approaches have given some hope. Available treatments considered Homeopathic, Ayurvedic, Unani, and other herbal-based drugs. There are new upcoming roles of nanoparticles in combating UTIs which needs further validation. The role of medicinal plant-based nanotechnology approaches has shown promising results. Therefore, there must be active research in phyto-based therapies of UTIs, such as Ayurvedic Biology.
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http://dx.doi.org/10.3390/molecules25235593 | DOI Listing |
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January 2025
Faculty of Biotechnologies (BioTech), ITMO University, 9 Lomonosova Street, 191002, Saint Petersburg, Russia.
Antimicrobial peptides (AMPs) are small, positively charged biomolecules produced by various organisms such as animals, microbes, and plants. These AMPs play a significant role in defense mechanisms and protect from adverse conditions. The emerging problem of drug resistance in microbes poses a global health challenge in treating diseases.
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December 2024
Modelling Program Division, Office of Science and Technology Integration, National Weather Service, NOAA, Silver Spring, MD, USA.
Phytoremediation is an eco-friendly, sustainable way to clean up the environment using green plants that effectively remove and degrade pollutants from soil, water, or air. Certain hyperaccumulator plants can effectively mitigate heavy metals, organic compounds, and radioactive substances through absorption, adsorption, and transformation. This method offers a cost-effective and esthetically pleasing alternative to traditional remediation techniques, contributing to the restoration of contaminated ecosystems.
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December 2024
Pharmaceutical Sciences Department, College of Pharmacy, QU Health, Qatar University, P.O. Box 2713, Doha, Qatar. Electronic address:
Amygdalin is a plant-based cyanogenic glycoside that has been the subject of both scientific interest and controversy for decades. Traditionally used in alternative medicine for its diverse biological activities, including anticancer, where amygdalin has been explored in complementary therapy. However, clinical utilization of amygdalin remains contentious due to concerns about its safety, primarily the release of hydrogen cyanide during its metabolism.
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December 2024
Department of Biotechnology, Motilal Nehru National Institute of Technology Allahabad, Prayagraj 211004, Uttar Pradesh, India. Electronic address:
The food demand to support the growing population worldwide is expected to increase up to 60 % by 2050. But, various abiotic stress including heat, drought, salinity, and heavy metal stress are becoming more prevalent due to global warming and seriously affecting the crop productivity. Nanotechnology has a great potential to solve this issue, as various nanoparticles (NPs) with their unique physical and chemical characteristics, have shown promising ability to enhance the stress tolerance and subsequently, improving the plant growth and development.
View Article and Find Full Text PDFCurr Drug Deliv
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Faculty of Pharmaceutical Science, Assam down town University, Sankar Madhab Path, Gandhi Nagar, Panikhaiti, Guwahati 781026, Assam, India.
Plant bioactive are being used since the early days of medicinal discovery for their various therapeutic activities and are safer compared to modern medicines. According to World Health Organization (WHO), approximately 180,000 deaths from burns occur every year with the majority in countries. Recent years have witnessed significant advancements in this domain, with numerous plant bioactive and their various nanoformulations demonstrating promising preclinical burn wound healing activity and identified plant-based nanotechnology of various materials through some variations of cellular mechanisms.
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