Could Periodontal Disease through Periopathogen be an Aggravating Factor for Gastric Cancer?

Periodontal disease affects the supporting tissues of the teeth, being a chronic inflammatory disease caused by specific microorganisms from subgingival biofilm. is a Gram-negative anaerobic bacterium that acts as a periodontal pathogen, being an important factor in linking Gram-positive and Gram-negative bacteria in the periodontal biofilm, but its involvement in systemic diseases has also been found. Several studies regarding the implication of in gastro-enterological cancers have been conducted. The present review aims to update and systematize the latest information about in order to evaluate the possibility of an association between periodontal disease and the evolution of gastroenterological cancers through the action of , highlighting gastric cancer. This would motivate future research on the negative influence of periodontal pathology on the evolution of gastric cancer in patients suffering from both pathologies.