Objectives: Peritoneal mesothelial cysts have been reported under various terms, including benign cystic mesothelioma, usually in the form of case reports/series, whereas extraperitoneal cases are rarely reported. Our objective was to report the detailed characteristics of cystic lesions of the serosal cavities.
Methods: We retrospectively examined the clinicopathologic findings of a series of mesothelial cystic lesions (n = 79).
Results: Most cases (n = 68, 86%) concerned the peritoneum, whereas 11 (14%) concerned the pericardium. No pleural cases were found. A total of 51 (64.5%) lesions were solitary, whereas 28 (35.5%) were multiple. Peritoneal lesions harbored a plump eosinophilic mesothelium and a loose connective stroma, whereas pericardial lesions showed a cuboidal/flattened mesothelium, collagenous stroma, intense inflammation, and other tissue types, like adipose and muscle tissue. Solitary peritoneal lesions are usually extrapelvic and found in older patients incidentally during other surgeries, whereas multiple lesions are found in younger patients and usually in the pelvis. The lesions show a benign clinical course with rare recurrences but no malignant transformation.
Conclusions: Most mesothelial cysts are peritoneal and rarely pericardial. Peritoneal cysts differ from pericardial cysts. Peritoneal solitary lesions differ from multiple lesions, also suggesting their pathogenetic differences.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/ajcp/aqaa189 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
A Tale of Two Cysts: A Histopathological Case Report of Epithelial and Mesothelial Splenic Cysts.
Cureus
December 2024
Research Institute, Medical University of Pleven, Pleven, BGR.
Splenic cysts are rare medical conditions, and their incidence is dominated by parasitic types. Non-parasitic splenic cysts, whether true cysts (with a cellular lining of the cystic wall) or pseudocysts (without a cellular lining), are significantly rarer than parasitic ones. Their etiology is not fully established, with fetal remnant development, metaplasia, and mesothelial invagination being widely accepted possible mechanisms.
View Article and Find Full Text PDFMesothelial Cyst in the Uterine Myometrium: A Rare Localization.
Cureus
December 2024
Department of Obstetrics and Gynecology, Kastamonu Training and Research Hospital, Kastamonu, TUR.
Article Synopsis
- Mesothelial cysts in the uterus are extremely rare; a 41-year-old woman experienced abdominal pain and imaging revealed a cystic mass in her uterus.
- The patient underwent laparoscopic surgery, where a 7 cm cystic lesion was found in the uterine wall.
- Pathological tests confirmed it was a mesothelial cyst, emphasizing that these cysts can resemble other conditions and are best diagnosed through surgical removal and examination.
A case report of a rare etiology of an abdominal cystic lesion in adults: Peritoneal inclusion cysts.
Int J Surg Case Rep
January 2025
Department of Visceral and Digestive Surgery, Monastir University Hospital, Monastir, Tunisia.
Introduction And Importance: Peritoneal inclusion cysts (PICs), also known as peritoneal mesothelial cysts, are rare, benign cystic lesions primarily occurring in the abdominopelvic cavity of premenopausal women with histories of pelvic surgery or inflammation. These cysts can present with nonspecific symptoms and may mimic other abdominal pathologies, making diagnosis challenging.
Case Presentation: A 41-year-old male with no significant medical history, who experienced progressive nonspecific abdominal pain over several months.
A Round Ligament Mesothelial Cyst Imitating an Inguinal Hernia in a Woman of Reproductive Age.
Acta Med Acad
September 2024
Second Department of Surgery, 251 Hellenic Air Force General Hospital, Athens, Greece.
Objective: A wide range of lesions, including a mesothelial cyst of the uterine round ligament, are included in the differential diagnosis of a groin mass. Our study emphasizes the rarity of this ailment and the significance of correct preoperative diagnosis in guiding our treatment approach.
Case Report: A 43-year-old female patient, presented to our hospital with a five-year history of swelling and slight discomfort in the right groin.
Diagnostic Journey From Suspected Ovarian Mass to Rare Mesothelial Cyst.
Cureus
October 2024
Obstetrics and Gynecology, Northwestern University Feinberg School of Medicine, Geneva, USA.
Article Synopsis
- Mesothelial cysts are benign cysts that arise from mesothelial cells, commonly occurring in women of reproductive age, but can also affect men and children.
- A case study of a 38-year-old woman with a suspected ovarian cyst revealed complex cystic structures that turned out to be a mesothelial-lined cyst after surgical exploration and pathological examination.
- Although rare and non-cancerous, mesothelial cysts should be considered in the diagnosis of pelvic cysts to avoid misdiagnosis and to ensure proper treatment; further research is needed regarding their impact on fertility.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!