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Development of a Novel Electrochemical Immunosensor for Rapid and Sensitive Detection of Sesame Allergens Ses i 4 and Ses i 5.
Foods
January 2025
School of Food and Biological Engineering, Engineering Research Center of Bio-Process of Ministry of Education, Anhui Province Laboratory of Agricultural Products Modern Processing, Hefei University of Technology, Hefei 230009, China.
Due to their lipophilicity and low content, the major sesame oleosin allergens, Ses i 4 and Ses i 5, are challenging to identify using conventional techniques. Then, a novel unlabeled electrochemical immunosensor was developed to detect the potential allergic activity of sesame oleosins. The voltammetric immunosensor was constructed using a composite of gold nanoparticles (AuNPs), polyethyleneimine (PEI), and multi-walled carbon nanotubes (MWCNTs), which was synthesized in a one-pot process and modified onto a glass carbon electrode to enhance the catalytic current of the oxygen reduction reaction.
View Article and Find Full Text PDFNatural history of sesame allergy in pediatric patients: Insight from a retrospective analysis.
Pediatr Allergy Immunol
January 2025
Department of Pediatric Allergy, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
Background: Sesame allergy (SA) is a growing concern because of its association with severe reactions and the limited knowledge of long-term outcomes.
Objective: This retrospective study aimed to identify the risk factors influencing persistent SA (PSA) in children to improve management and select suitable candidates for oral immunotherapy (OIT).
Methods: We analyzed the electronic medical records of 84 children with confirmed SA, as defined by consistent clinical reactions and immunoglobulin E (IgE)-mediated sensitization.
Interpreting epidemiologic distribution of total and specific IgE levels for food allergy in Southern China from 2004 to 2023: understanding the mechanisms and focusing on prevention.
BMC Public Health
October 2024
Department of Clinical Laboratory of the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease, National Center for Respiratory Medicine, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, Guangzhou, 510120, China.
Background: The burgeoning prevalence of food allergy-related diseases is closely associated with geographical allergen distribution and societal lifestyle paradigms. This study aims to shed light on the distribution patterns of specific IgE (sIgE) and total IgE (tIgE) reactivity to common food allergens in the Southern Chinese populace.
Methods: Employing an analytical technique spanning two decades, we conducted specific IgE and total IgE on serum samples harvested from patients with food allergy-related pathologies at First Affiliated Hospital of Guangzhou Medical University from 2004 to 2023.
Air pollution is associated with persistent peanut allergy in the first 10 years.
J Allergy Clin Immunol
December 2024
Murdoch Children's Research Institute, Melbourne, Australia; Department of Paediatrics, University of Melbourne, Parkville, Australia. Electronic address:
Background: The role of air pollution in eczema and food allergy development remains understudied.
Objective: We aimed to assess whether exposure to air pollution is associated with eczema and food allergies in the first 10 years of life.
Methods: HealthNuts recruited a population-based sample of 1-year-old infants who were followed up at ages 4, 6, and 10 years.
Oral immunotherapy improves the quality of life of adults with food allergy.
Allergy Asthma Clin Immunol
October 2024
The Institute of Allergy, Immunology and Pediatric Pulmonology, Shamir Medical Center (Former Assaf Harofeh), 71300, Be'er Ya'akov, Israel.
Article Synopsis
- Oral immunotherapy (OIT) has shown to notably enhance the quality of life for children with food allergies, but its effects on adults have not been as extensively researched.
- In a study involving adults with food allergies who underwent OIT, significant improvements in quality of life were observed using the Food Allergy Quality of Life Questionnaire, particularly in areas related to allergen avoidance, emotional impact, and overall health.
- The results support the effectiveness of OIT in enhancing the quality of life for adults with food allergies, indicating a need for its broader application in this population.
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