AI Article Synopsis
- * The study used data from the HF-ACTION trial to explore the relationship between BSA and the ability to reach target doses of effective treatments like beta-blockers and ACE inhibitors.
- * It also looked at how these target doses, clinical outcomes, and BSA connect and interact with each other.
Article Abstract
Recognizing that body surface area (BSA) is a commonly used metric to inform medication dosing across fields of medicine, it is possible that patients with heart failure with reduced ejection fraction (HFrEF) with higher BSA may be more likely to tolerate higher doses of GDMT. Using the HF-ACTION trial, we examined (1) the relationship between BSA and achievement of target dosing of evidence-based beta-blocker and angiotensin-converting enzyme inhibitor (ACEI) therapy, and (2) the associations and interactions between target dosing, clinical outcomes, and BSA.
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| http://dx.doi.org/10.1016/j.ahj.2020.11.003 | DOI Listing |
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