A single-molecule view of telomerase regulation at telomeres.

Mol Cell Oncol

Skirball Institute of Biomolecular Medicine, NYU School of Medicine, New York, NY, USA.

Published: September 2020

Telomerase plays a key role in the immortalization of cancer cells by maintaining telomeres length. Using single-molecule imaging of telomerase RNA molecules in cancer cells, we recently reported novel insights into the role of Cajal bodies in telomerase biogenesis and the regulation of telomerase recruitment to telomeres.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7671040PMC
http://dx.doi.org/10.1080/23723556.2020.1818537DOI Listing

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