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Development and Characterization of Hyaluronic Acid Graft-Modified Polydopamine Nanoparticles for Antibacterial Studies.
Polymers (Basel)
January 2025
School of Biomedical Engineering and Imaging, Xianning Medical College, Hubei University of Science and Technology, Xianning 437100, China.
The problem of antibiotic abuse and drug resistance is becoming increasingly serious. In recent years, polydopamine (PDA) nanoparticles have been recognized as a potential antimicrobial material for photothermal therapy (PTT) due to their excellent photothermal conversion efficiency and unique antimicrobial ability. PDA is capable of rapidly converting light energy into heat energy under near-infrared (NIR) light irradiation to kill bacteria efficiently.
View Article and Find Full Text PDFRisk Factors Associated with Hemoparasites in Dual-Purpose Cattle of Colombia.
Pathogens
January 2025
Centro de Investigación Turipaná, Corporación Colombiana de Investigación Agropecuaria AGROSAVIA, km 13 vía Montería, Cereté 230550, Colombia.
Hemoparasitic diseases represent a significant problem with a considerable impact on tropical and subtropical areas of the world. These conditions cause economic losses associated with multi-organic failure and even the death of animals. In these areas, the hemoparasites are transmitted in an enzootic cycle when infectious cattle, such as persistently infected animals, including cows, contribute to the success of transmission.
View Article and Find Full Text PDFGenetic Algorithm-Enhanced Direct Method in Protein Crystallography.
Molecules
January 2025
Department of Physics, School of Physical Science and Technology, Ningbo University, Ningbo 315211, China.
Direct methods based on iterative projection algorithms can determine protein crystal structures directly from X-ray diffraction data without prior structural information. However, traditional direct methods often converge to local minima during electron density iteration, leading to reconstruction failure. Here, we present an enhanced direct method incorporating genetic algorithms for electron density modification in real space.
View Article and Find Full Text PDFChallenges in Humoral Immune Response to Adeno-Associated Viruses Determination.
Int J Mol Sci
January 2025
Federal Research Center for Original and Prospective Biomedical and Pharmaceutical Technologies, 8 Baltiyskaya Street, Moscow 125315, Russia.
Adeno-associated viruses (AAVs) are non-pathogenic, replication-deficient viruses that have gained widespread attention for their application as gene therapy vectors. While these vectors offer high transduction efficiency and long-term gene expression, the host immune response poses a significant challenge to their clinical success. This review focuses on the obstacles to evaluating the humoral response to AAVs.
View Article and Find Full Text PDFIs the Beck Depression Inventory (BDI) a Useful Tool for Predicting IVF Success?
Medicina (Kaunas)
January 2025
Clinic for Obstetrics and Gynecology, 11000 Belgrade, Serbia.
: Infertility is a global problem. The interaction between depression and infertility seems bidirectional, and depression may negatively influence IVF outcomes. The Beck Depression Inventory (BDI) is one of the most extensively used instruments for diagnosing depression.
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