AI Article Synopsis
- - The study aimed to investigate how lifestyle interventions, specifically diet and exercise, influence the occurrence of gestational diabetes mellitus (GDM) in pregnant women with a BMI of 25 or higher, using data from the LIFE-Moms consortium.
- - Despite early lifestyle changes reducing excess weight gain during pregnancy, the interventions did not significantly impact the overall diagnosis rate of GDM when compared to standard care.
- - Women diagnosed with GDM were generally heavier and had higher rates of obesity and dysglycemia before pregnancy, indicating that initial health status played a key role in GDM outcomes.
Article Abstract
Aims: To examine the effect of lifestyle (diet and physical activity) interventions on the prevalence of GDM, considering the method of GDM ascertainment and its association with early pregnancy characteristics and maternal and neonatal outcomes in the LIFE-Moms consortium.
Methods: LIFE-Moms evaluated the effects of lifestyle interventions to optimize gestational weight gain in 1148 pregnant women with BMI ≥ 25 kg/m and without known diabetes at enrollment, compared with standard care. GDM was assessed between 24 and 31-weeks gestation by a 2-hour, 75-gram OGTT or by local clinical practice standards.
Results: Lifestyle interventions initiated prior to 16 weeks reduced early excess GWG compared with standard care (0.35 ± 0.24 vs 0.43 ± 0.26 kg per week, p=<0.0001) but did not affect GDM diagnosis (11.1% vs 11.6%, p = 0.91). Using the 75-gram, 2-hour OGTT, 13. 0% of standard care and 11.0% of the intervention group had GDM by the IADPSG criteria (p = 0.45). The 'type of diagnostic test' did not change the result (p = 0.86). Women who developed GDM were significantly heavier, more likely to have obesity, and more likely to have dysglycemia at baseline.
Conclusion: Moderate-to-high intensity lifestyle interventions grounded in behavior change theory initiated between 9 and 16-weeks gestation did not affect the prevalence of GDM despite reducing early GWG. CLINICALTRIALS.GOV: NCT01545934, NCT01616147, NCT01771133, NCT01631747, NCT01768793, NCT01610752, NCT01812694.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9041868 | PMC |
| http://dx.doi.org/10.1016/j.diabres.2020.108549 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Behavior-change lifestyle interventions for the treatment of obesity in children and adolescents: A scoping review.
Ann N Y Acad Sci
December 2024
National Institute of Health Data Science, Peking University, Beijing, China.
Behavior-change lifestyle interventions are fundamental in children and adolescent obesity management. This scoping review discusses optimal behavior-change lifestyle interventions in the treatment of overweight and obesity in children and adolescents. A literature search on diet, physical activity, and behavioral intervention for obesity treatment in children and adolescents aged 0-19 years was conducted in the Cochrane Library, MEDLINE (OVID), EMBASE, and ClinicalTrials.
View Article and Find Full Text PDFFactors Influencing the Outcome, Mechanism, and Implementation of Motivational Interviewing After Hip Fracture: A Qualitative Analysis.
J Geriatr Phys Ther
December 2024
School of Psychology and Public Health, La Trobe University, Victoria, Australia.
Background And Purpose: Motivational interviewing, an evidence-based person-centered counseling style, may help to facilitate increased mobility and physical activity after hip fracture. We explored contextual factors influencing the outcome, mechanism, and implementation of motivational interviewing after hip fracture.
Methods: A qualitative study was completed using an interpretive description framework.
Gut microbiome-gut brain axis-depression: interconnection.
World J Biol Psychiatry
December 2024
Institute of Biosciences and Technology, MGM University, Aurangabad, India.
Objectives: The relationship between the gut microbiome and mental health, particularly depression, has gained significant attention. This review explores the connection between microbial metabolites, dysbiosis, and depression. The gut microbiome, comprising diverse microorganisms, maintains physiological balance and influences health through the gut-brain axis, a communication pathway between the gut and the central nervous system.
View Article and Find Full Text PDFMediterranean diet and brain functional connectivity in a population without dementia.
Front Neuroimaging
December 2024
First Department of Neurology, Aiginition Hospital, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.
Introduction: Adjustable lifestyle factors, such as diet, are associated with cognitive functions, structural and functional brain measures, but the association between the functional connectivity (FC) and the Mediterranean Diet (Medicine) in population without dementia is yet to be explored.
Methods: The association between MeDi and brain FC in 105 individuals without dementia aged 63 (SD ± 8.72) years old who underwent brain MRI including resting-state (rs) functional MRI (fMRI) was examined.
A higher global diet quality score is associated with lower risk of obesity among male university students in Lebanon: a pilot study.
Front Nutr
December 2024
Department of Nutrition and Food Sciences, Faculty of Agricultural and Food Sciences, American University of Beirut, Beirut, Lebanon.
Objective: This pilot study aims to assess the diet quality amongst Lebanese male university students using the Global Diet Quality Score (GDQS), identify its association with obesity, and determine the key drivers of consumption of foods associated with higher NCDs risk.
Methods: A cross-sectional survey was conducted using a convenience sampling approach, comprising 385 male students aged between 18 and 24 years at the American University of Beirut. Dietary data was collected using 24-h recall, where participants detailed all foods and beverages consumed in the past 24 h, including portion sizes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!