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http://dx.doi.org/10.1002/mds.28374 | DOI Listing |
Behav Res Methods
January 2025
Department Neurophysics, Philipps-Universität Marburg, Fachbereich Physik, AG Neurophysik, Karl-Von-Frisch-Straße 8a, 35043, Marburg, Lahnberge, Germany.
The analysis of eye movements is a noninvasive, reliable and fast method to detect and quantify brain (dys)function. Here, we investigated the performance of two novel eye-trackers-the Thomas Oculus Motus-research mobile (TOM-rm) and the TOM-research stationary (TOM-rs)-and compared them with the performance of a well-established video-based eye-tracker, i.e.
View Article and Find Full Text PDFExp Brain Res
January 2025
Department of Neurology and Suzhou Clinical Research Center of Neurological Disease, The Second Affiliated Hospital of Soochow University, No. 1055, Sanxiang Road, Suzhou, 215004, Jiangsu Province, People's Republic of China.
This study investigated the relationship between eye movement parameters and cognitive function in patients with mild to moderate Alzheimer's disease (AD). A total of 80 patients with AD (mild and moderate) and 34 normal controls (NC) participated. Neuropsychological assessments were conducted using the Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA), while eye movements were recorded using eye-tracking technology.
View Article and Find Full Text PDFNPJ Parkinsons Dis
December 2024
Centre for Neuroscience Studies, Queen's University, Kingston, ON, Canada.
Oculomotor behaviour changes in patients with Parkinson's disease (PD) are a promising source of prodromal disease markers. Capitalizing on this phenomenon to facilitate early diagnosis requires oculomotor assessment in prodromal cohorts. We examined oculomotor behaviour in non-manifesting LRRK2 G2019S mutation carriers (LRRK2-NM), who have heightened PD risk.
View Article and Find Full Text PDFPsychophysiology
January 2025
Department of Psychology and Research Institute for Health Sciences (iUNICS), University of the Balearic Islands, Palma, Spain.
Unexpected sounds have been shown to trigger a global and transient inhibition of motor responses. Recent evidence suggests that eye movements may also be inhibited in a similar way, but it is not clear how quickly unexpected sounds can affect eye-movement responses. Additionally, little is known about whether they affect only voluntary saccades or also reflexive saccades.
View Article and Find Full Text PDFJ Alzheimers Dis
December 2024
Department of Neurology, The Second Hospital of Hebei Medical University, Shijiazhuang, China.
Background: The early identification of Alzheimer's disease (AD) benefits patients, so creating a simple and convenient method is crucial for diagnosing early symptoms.
Objective: To offer a potential approach for the early detection of both AD and mild cognitive impairment (MCI).
Methods: Eye movement data from 66 patients were divided into three groups, including healthy control group (HC), MCI group, and AD group.
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