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| http://dx.doi.org/10.1007/s10620-020-06731-3 | DOI Listing |
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Article Synopsis
- The article presents a clinical case of a young patient with HPV-associated penile intraepithelial neoplasia (PIN), specifically the erythematous form of bowenoid papulosis.
- It highlights the issues of delayed diagnosis due to improper diagnostic approaches and a lack of awareness among doctors about cancer-related diseases.
- The piece emphasizes the significance of early detection in preventing progression to more severe conditions like squamous cell penile carcinoma, detailing the different subtypes of PIN and their varying risks of leading to cancer.
Cervical intraepithelial neoplasia and cervical cytology in pregnancy.
J Pathol Transl Med
November 2024
Department of Pathology, CHA University School of Medicine, CHA Gangnam Medical Center, Seoul, Korea.
Cervical cancer screening during pregnancy presents unique challenges for cytologic interpretation. This review focuses on pregnancy-associated cytomorphological changes and their impact on diagnosis of cervical intraepithelial neoplasia (CIN) and cervical cancer. Pregnancy-induced alterations include navicular cells, hyperplastic endocervical cells, immature metaplastic cells, and occasional decidual cells or trophoblasts.
View Article and Find Full Text PDFPhotodynamic therapy compared with loop electrosurgical excision procedure in patients with cervical high-grade squamous intraepithelial lesion.
Sci Rep
November 2024
Department of Obstetrics and Gynecology, Peking University Shenzhen Hospital, No.1120 Lianhua Road, Futian district, Shenzhen, 518036, Guangdong, China.
The study aimed to compare the effectiveness between Hiporfin-photodynamic therapy (PDT) and loop electrosurgical excision procedure (LEEP) in treating cervical high-grade squamous intraepithelial lesion (HSIL). We conducted a retrospective analysis of 104 women diagnosed with cervical HSIL at our hospital from April 2019 to July 2023. With 1:1 matched case-control, 52 cases received Hiporfin-PDT and 52 cases underwent LEEP.
View Article and Find Full Text PDFDistribution of 14 High-Risk HPV Types and p16/Ki67 Dual-Stain Status in Post-Colposcopy Histology Results: Negative, Low- and High-Grade Cervical Squamous Intraepithelial Lesions.
Cancers (Basel)
October 2024
Division of Clinical Pathology, Department of Clinical and Experimental Pathology, Wroclaw Medical University, Borowska 213, 50-556 Wroclaw, Poland.
Article Synopsis
- The study investigates the distribution of high-risk HPV types in low and high-grade cervical lesions to understand their role in cervical cancer progression.
- Using data from a large sample of screening tests, the researchers analyzed the prevalence of HPV types and dual staining status among different histological groups.
- Results showed significant differences in HPV 16 prevalence and dual staining positivity between high-grade lesions and lower-grade or negative cases, emphasizing the varying risks associated with cervical lesion grades.
Statistically Significant Associations Between HPV33, HPV35, and HPV56 With Anal HSIL in a Population of MSMLWH.
J Low Genit Tract Dis
January 2025
George Washington University, School of Public Health, Department of Epidemiology, Washington, DC.
Objective: The aim of the study is to determine the prevalence of high-risk human papillomavirus (hrHPV) genotypes in men who have sex with other men and are living with HIV and the factors associated with anal high-grade squamous intraepithelial lesions (HSIL).
Methods: Anal swabs were collected for hrHPV genotyping from a cross-sectional group ( N = 163) of eligible men who have sex with other men and are living with HIV attending a high-resolution anoscopy clinic. Persistent hrHPV infections were studied in a longitudinal subset ( n = 37).
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