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Ecthyma gangrenosum is a rare and severe skin disease that is typically accompanied by a systemic infection caused by Pseudomonas aeruginosa bacteria. It manifests as painful, necrotic lesions surrounded by redness and including a noticeable black eschar in the centre. The majority of ecthyma gangrenosum instances occur in immunocompromised individuals, such as those with significant underlying medical conditions or those who are neutropenic.

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Article Synopsis
  • Ecthyma gangrenosum (EG) is primarily a skin infection often seen in immunocompromised individuals, but it can also be caused by other bacteria or fungi in both immunocompromised and non-immunocompromised people.
  • A case study of a 75-year-old woman revealed severe respiratory distress due to influenza A H1N1, which later led to the development of EG with ulcerated skin lesions as complications.
  • The case highlights that EG can arise from various pathogens, emphasizing the need to consider fungal infections in such clinical scenarios.
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Article Synopsis
  • Leg ulcers, primarily located below the knee, can stem from various causes with around 80% resulting from chronic venous insufficiency (CVI) or peripheral arterial occlusive disease (PAOD), necessitating diverse medical specialists for treatment.
  • The diagnostic approach follows the ABCDE rule, which includes personalized history-taking, bacteriological testing, clinical exams, and additional tests to accurately identify the cause of the ulcer, such as vascular issues or other diseases.
  • Effective treatment relies on prompt differential diagnosis, highlighting the need for collaboration among different medical specialties due to the complexity of leg ulcers and the challenges posed by limited high-quality research.
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Perineal Ecthyma Gangrenosum.

J Cutan Med Surg

August 2024

Division of Dermatology, Department of Pediatrics, CHU Sainte-Justine, Universite de Montreal, Montreal, QC, Canada.

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