Introduction: The World Health Organization recommends that 1% to 3% of a country's population should donate blood to meet its demand and should focus on young people to achieve 100% voluntary blood donation. The aim of this study was to assess voluntary blood donation among Bahir Dar University students by using an integrated behavioral model.
Methods: An institution-based cross-sectional study was conducted on Bahir Dar University students from March 1-21, 2020. A multi-stage sampling technique was applied to select 625 study participants. Data were entered in Epi data version 3.1 and then exported to SPSS version 23.0 for analysis. Path analysis was done using Stata 15 to check the causal effect of the integrated behavioral model constructs on voluntary blood donation. Internal consistency and validity of constructs were checked using Cronbach's alpha and exploratory factor analysis, respectively. Multivariable linear and logistics regression were used to predict independent predictors on intention and voluntary blood donation, respectively. The significant independent predictor was declared at 95% confidence interval and P-value < 0.05.
Results: One hundred and four (16.8%) university students donated blood voluntarily. Being female (AOR = 1.92 (1.15-3.22)), being third year (AOR = 2.88 (1.55-5.35)), knowledge (AOR = 1.53 (1.32-1.77)), descriptive norm (AOR = 1.10 (1.01-1.12)) and intention (AOR = 1.42 (1.28-1.57)) were positively associated with blood donation. Injunctive norm (B = 0.06) and self-efficacy (B = 0.36) have significant association with intention. Intention, descriptive norm and knowledge have significant effect on blood donation with path coefficient 0.0, 0.09 and 0.48, respectively.
Conclusion: The magnitude of voluntary blood donation was low as compared to other similar studies. Descriptive norm, intention, knowledge, sex, year of study were significant predictors associated with voluntary blood donation. Therefore, behavioral change health communication strategies should develop to address these factors among the students. Researchers should conduct prospective analytical study design to examine the causal relationship of constructs of the model to develop better interventional strategy.
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http://dx.doi.org/10.2147/JBM.S277411 | DOI Listing |
J Virus Erad
December 2024
Center of Excellence in Clinical Virology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Chronic hepatitis B (HBV) and C (HCV) are major health challenges in Thailand, with Phetchabun province, a known HCV-endemic area, being a key target for elimination efforts. This study aimed to assess HBV prevalence and identify associated risk factors in this province. Data was collected from three cross-sectional population studies: (1) adults in 2015 (n = 1,667, age 30-64 years), (2) young adults in 2017 (n = 1,453, age 18-30 years), both from high HCV-endemic districts, and (3) a province-wide study in 2018 (n = 4,769, age 35-64 years).
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December 2024
General Practice, Eradah And Mental Health Complex, Taif, SAU.
Background: Blood donation plays a critical role in public health, yet long-term donors (donating at least twice per year, for at least three years) often face challenges related to psychological adjustment and quality of life. Digital health tools could offer innovative solutions to address these issues by providing personalized support, tracking, and mental health interventions.
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Mol Ther Oncol
December 2024
Cancer Immunotherapy Group, Oncobell and iProCURE programs, IDIBELL-Institut Català d'Oncologia, 08907 L'Hospitalet de Llobregat, Barcelona, Spain.
Oncolytic viruses (OVs) are a promising therapeutic approach for cancer, although their systemic administration faces significant challenges. Mesenchymal stem cells have emerged as potential carriers to overcome these obstacles due to their tumor-tropic properties. This study investigates the use of menstrual blood-derived mesenchymal stem cells (MenSCs) as carriers for OVs in cancer therapy, focusing on enhancing their efficacy through different culture conditions.
View Article and Find Full Text PDFAnn Med
December 2025
Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive & Genetic Hospital of International Trust and Investment Corporation (CITIC)-Xiangya, Changsha, China.
Objectives: At present, most genetic tests or carrier screening are performed with blood samples, and the known carrier rate of disease-causing variants is also derived from blood. For semen donors, what is really passed on to offspring is the pathogenic variant in their sperm. This study aimed to determine whether pathogenic variants identified in the sperm of young semen donors are also present in their blood, and whether matching results for blood are consistent with results for sperm.
View Article and Find Full Text PDFJ Infect
January 2025
Department of Oncology and National Centre for HIV Malignancy, Chelsea and Westminster Hospital, London, UK; Centre for Immunology and Vaccinology, Department of Infectious Diseases, Imperial College, London, UK. Electronic address:
In solid organ transplant recipients (SOTRs), the oncogenic virus human herpesvirus-8 (HHV-8) also named Kaposi sarcoma herpesvirus (KSHV) causes four clinical diseases: Kaposi Sarcoma, Primary Effusion Lymphoma, Multicentric Castleman Disease (MCD), and KSHV inflammatory cytokine syndrome (KICS). This review outlines these clinical scenarios and discusses their management. Although HHV8 related disease in SOTR was first described more than three decades ago, there is a lack of data on treatment so much of the guidance is based on evidence in other immunodeficient patients, particularly people living with HIV.
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