Pluripotent pig embryonic stem cell lines originating from in vitro-fertilized and parthenogenetic embryos.

Stem Cell Res

Department of Agricultural Biotechnology, Animal Biotechnology Major, and Research Institute of Agriculture and Life Science, Seoul National University, Seoul 08826, Republic of Korea; Institute of Green Bio Science and Technology, Seoul National University, Pyeong Chang 25354, Republic of Korea. Electronic address:

Published: December 2020

Here, we report in vivo developmental competent pig embryonic stem cells (ESCs) originating from in vitro-fertilized and parthenogenetic embryos cultured in chemically defined culture media. The pig ESC lines expressed pluripotency markers and were capable of forming teratomas following subcutaneous injection into nude mice. These cell lines would be a useful resource for comparative developmental biology and agricultural biotechnology.

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http://dx.doi.org/10.1016/j.scr.2020.102093DOI Listing

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