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Article Synopsis
  • Cat scratch disease is caused by a Gram-negative bacillus from cat saliva or scratches, presenting primarily as localized swelling or regional lymph nodes.
  • Rare complications can occur, including serious issues affecting the liver and bones, such as hepatic abscesses and osteomyelitis, especially in children with a history of cat exposure.
  • A 2-year-old boy with a severe case was treated successfully with azithromycin and rifampin after showing symptoms like fever and musculoskeletal pain, highlighting the importance of abdominal imaging in diagnostics for this condition.
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Paws and Pathogens: A Multidisciplinary Approach Through Endocarditis and Hepatosplenic T-Cell Lymphoma.

J Investig Med High Impact Case Rep

July 2024

Division of Infectious Diseases, Department of Medicine, Medical College of Georgia, Wellstar MCG Health, Augusta, GA, USA.

Article Synopsis
  • Gram-negative coccobacilli are important pathogens that can lead to zoonotic infections in humans, especially causing infective endocarditis, which can be hard to diagnose.
  • A 23-year-old male initially misdiagnosed with lymphoma was actually suffering from blood culture-negative endocarditis linked to these bacteria, showing symptoms like fevers, pancytopenia, and heart issues despite negative blood tests.
  • The case emphasizes the need for careful consideration of these pathogens in patients with suspected endocarditis and highlights the importance of serological testing and a comprehensive treatment strategy for better patient outcomes.
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Unusual presentation of cat scratch disease: case report.

Eur J Clin Microbiol Infect Dis

August 2024

Department of Pediatrics, Division of Pediatric Infectious Diseases, Faculty of Medicine, Marmara University, Fevzi Cakmak, Muhsin Yazicioglu St, No:10, Floor: 6, Istanbul, Turkey.

Cat scratch disease (CSD) is an infection caused by Bartonella henselae, presents with non-specific symptoms like lymphadenopathy, fever, and fatigue. It can progress to disseminated disease, leading to complications such as liver and splenic micro abscesses, osteomyelitis, encephalitis, and uveitis. Diagnosis is challenging due to varied presentations and limited tests.

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Systemic infection, also known as cat-scratch disease (CSD), presents a diagnostic challenge due to the variability of clinical manifestations and the potential for serological cross-reactivity with other organisms. This study aimed to retrospectively analyze the epidemiological, clinical, laboratory, and imaging characteristics of pediatric patients diagnosed with systemic infection, to improve understanding and facilitate timely diagnosis and treatment. We conducted a 10-year retrospective study at the "Louis Turcanu" Children's Emergency Hospital and private clinics in Timisoara, Romania, reviewing records for confirmed cases of infection from January 2014 to January 2024.

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Article Synopsis
  • Bartonelloses are diseases caused by Bartonella bacteria, transmitted to humans through blood-sucking insects, leading to conditions like bacillary angiomatosis and cat scratch disease.
  • A review of cases involving bartonelloses and blood cancers in HIV-negative patients identified 15 relevant cases, highlighting various symptoms such as chronic fever and lymphadenopathy.
  • Most patients responded well to antibiotic treatment, but clinicians need to be vigilant for Bartonella infections, especially in immunocompromised individuals.
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