Objectives: To assess (1) the relationship of consumers' assessment of overall nursing home quality to their assessment of specific dimensions of quality; and (2) the implications of this relationship for composite quality measures in Nursing Home Compare.
Design: A survey conducted in 2017 elicited respondents' assessments of the quality of overall care and 13 specific dimensions of care.
Settings And Participants: The sample consisted of 4449 respondents who either resided in a nursing home or had a family member who resided in a nursing home during the 6 months before the survey.
Methods: We estimated regression models to infer the relationship between consumers' assessments of overall quality and 13 specific dimensions of quality. The regression coefficients, indicating the implicit importance/weight assigned by respondents to each dimension as a component of the consumers' assessment of overall quality, were used to create a prototype composite quality measure.
Results: For long-stay residents, 8 of the 13 quality dimensions were significantly associated with their overall ratings of quality. Five dimensions achieved significance for short-stay residents. The magnitude of importance weights varied substantially across dimensions of care.
Conclusions And Implications: Our findings suggest that Nursing Home Compare could be improved by augmenting the technical information in the 5-Star composite measure with consumers' assessments of the additional, nontechnical dimensions of quality.
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http://dx.doi.org/10.1016/j.jamda.2020.10.004 | DOI Listing |
Magn Reson Med
March 2025
Center for Magnetic Resonance Research, Radiology, Medical School, University of Minnesota, Minneapolis, Minnesota, USA.
Purpose: To propose a two-step, nonlocal principal component analysis (PCA) method and demonstrate its utility for denoising complex diffusion MR images with a few diffusion directions.
Methods: A two-step denoising pipeline was implemented to ensure accurate patch selection even with high noise levels and was coupled with data preprocessing for g-factor normalization and phase stabilization before data denoising with a nonlocal PCA algorithm. At the heart of our proposed pipeline was the use of a data-driven optimal shrinkage algorithm to manipulate the singular values in a way that would optimally estimate the noise-free signal.
Neurol Neurochir Pol
March 2025
Department of Neurosurgery, Medical University of Gdansk, Gdansk, Poland.
Introduction: This study aimed to identify predictive factors for long-term incomplete nidus obliteration following stereotactic radiosurgery (SRS) for brain arteriovenous malformations (AVMs).
Material And Methods: A systematic search across the PubMed, Web of Science, and Scopus databases identified observational studies reporting such factors. Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were followed.
Mol Pharm
March 2025
Merck & Co., Inc., Rahway, New Jersey 07065, United States.
This is the fourth paper in a series describing an inhalation biopharmaceutics classification system (iBCS), an initiative supported by the Product Quality Research Institute. The paper examines the application of the inhalation Biopharmaceutics Classification System (iBCS) through the drug discovery, development, and postapproval phases for orally inhaled drug products (OIDP) and for the development of generic OIDPs. We consider the implication of the iBCS class in terms of product performance and identify the practical gaps that must be filled to enable the classification system to be adopted into day-to-day practice.
View Article and Find Full Text PDFJ Sci Food Agric
March 2025
Instituto de Ciencias de la Vid y del Vino (CSIC, Gobierno de la Rioja), Universidad de La Rioja, Departamento de Viticultura, Logroño, Spain.
Background: Applying organic amendments to vineyard soil improves soil properties and vine development by increasing soil water retention and nutrient content. However, little is known about how organic mulches modify grapevine phenolic composition. This study analysed the phenolic profile in the leaves, canes, and grape skins of Tempranillo over 3 years in two vineyard locations with three organic mulches: spent mushroom compost (SMC), grapevine pruning debris (GPD) and straw (STR), as well as two conventional soil practices: herbicide (HERB) and tillage (TILL).
View Article and Find Full Text PDFBone Joint Res
March 2025
Department of Orthopedics, The Affiliated Changzhou Second People's Hospital of Nanjing Medical University, Changzhou, China.
Aims: Osteoarthritis (OA) is a widespread chronic degenerative joint disease with an increasing global impact. The pathogenesis of OA involves complex interactions between genetic and environmental factors. Despite this, the specific genetic mechanisms underlying OA remain only partially understood, hindering the development of targeted therapeutic strategies.
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