AI Article Synopsis

  • * These painful ulcers can lead to poverty and, in some cases, permanent bone malformations in affected individuals.
  • * Improving our understanding of CUD could help create better diagnostic tools and more effective treatments for these debilitating infections.

Article Abstract

Cutaneous ulcers in the tropics are a painful and debilitating condition that anchors people into poverty. In rural regions of the South Pacific, infectious cutaneous ulcers are caused mainly by bacteria, including Treponema pallidum pertenue (yaws), Haemophilus ducreyi, and polymicrobial ulcers. For this group of infections the term cutaneous ulcer disease (CUD) is proposed. Some infections can cause malformations on the bone that have a permanent impact on lives in endemic communities. Better characterization of CUD may help design diagnostic tools and more effective antimicrobial therapies. This review updates the knowledge of CUD and discusses optimized terminology and syndromic management.

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http://dx.doi.org/10.1016/j.det.2020.08.002DOI Listing

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