AI Article Synopsis

  • This study explored the relationship between dietary inflammatory index (DII) and obesity-related factors among Iranian women, finding that an anti-inflammatory diet was associated with lower fat mass and higher fat-free mass.
  • After adjustments for factors like age and physical activity, women on anti-inflammatory diets had significantly different body compositions compared to those on pro-inflammatory diets.
  • Additionally, lower DII levels correlated with reduced serum levels of monocyte chemoattractant protein-1 (MCP-1), indicating a potential link to inflammation, suggesting that dietary choices could influence obesity and health outcomes.

Article Abstract

Objective: Although, several studies have illustrated that there is a relation between dietary inflammatory index (DII) with obesity-related parameters, and inflammation, their results were controversial. This study aimed to investigate this relationship among Iranian women.

Results: Multivariable linear regression showed that fat mass was 0.14 kg lower in the anti-inflammatory diet group, with respect to the pro-inflammatory group, after adjusting covariates such as age, physical activity, economic and job status (β = - 0.142, 95% CI - 4.44, - 1.71, P = 0.03). Fat-free mass (FFM) was 1.5 kg more in the anti-inflammatory diet group, compared to the pro-inflammatory diet group, after adjusting for potentials cofounders (β = 1.50, 95% CI 0, 3.01, p = 0.05). Furthermore, after adjusting for potentials cofounders, it was revealed that the subjects with lower DII had lower monocyte chemoattractant protein-1 (MCP-1) levels in serum (β = - 18.81, 95% CI - 35.84, - 1.79, p = 0.03). These findings suggest an inverse and significant relationship between DII and FFM and also DII is directly related to Fat mass and the level of MCP-1. This finding can be used for developing interventions that aim to promote healthy eating to prevent inflammation and non-communicable disease development among obese females.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7684955PMC
http://dx.doi.org/10.1186/s13104-020-05390-xDOI Listing

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