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Learning Transversus Abdominis Activation in Older Adults with Chronic Low Back Pain Using an Ultrasound-Based Wearable: A Randomized Controlled Pilot Study.
J Funct Morphol Kinesiol
January 2025
Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, 13347 Berlin, Germany.
: Chronic low back pain (CLBP) is prevalent among older adults and leads to significant functional limitations and reduced quality of life. Segmental stabilization exercises (SSEs) are commonly used to treat CLBP, but the selective activation of deep abdominal muscles during these exercises can be challenging for patients. To support muscle activation, physiotherapists use biofeedback methods such as palpation and ultrasound imaging.
View Article and Find Full Text PDFThree-dimensional structure of entire hydrated murine hearts at histological resolution.
Sci Rep
January 2025
Institute for X-ray Physics, Georg-August University Göttingen, Friedrich-Hund-Platz 1, 37077, Göttingen, Germany.
Imaging the entire cardiomyocyte network in entire small animal hearts at single cell resolution is a formidable challenge. Optical microscopy provides sufficient contrast and resolution in 2d, however fails to deliver non-destructive 3d reconstructions with isotropic resolution. It requires several invasive preparation steps, which introduce structural artefacts, namely dehydration, physical slicing and staining, or for the case of light sheet microscopy also clearing of the tissue.
View Article and Find Full Text PDFAutomated extracellular volume fraction measurement for diagnosis and prognostication in patients with light-chain cardiac amyloidosis.
PLoS One
January 2025
Phantomics, Inc., Seoul, South Korea.
Aims: T1 mapping on cardiac magnetic resonance (CMR) imaging is useful for diagnosis and prognostication in patients with light-chain cardiac amyloidosis (AL-CA). We conducted this study to evaluate the performance of T1 mapping parameters, derived from artificial intelligence (AI)-automated segmentation, for detection of cardiac amyloidosis (CA) in patients with left ventricular hypertrophy (LVH) and their prognostic values in patients with AL-CA.
Methods And Results: A total of 300 consecutive patients who underwent CMR for differential diagnosis of LVH were analyzed.
The prevalence of gas exchange data processing methods: a semi-automated scoping review.
Int J Sports Med
January 2025
Department of Kinesiology.
Cardiopulmonary exercise testing involves collecting variable breath-by-breath data and sometimes requiring data processing of outlier removal, interpolation, and averaging before later analysis. These data processing choices, such as averaging duration, affect calculated values such as ˙VOmax. However, assessing the implications of data processing without knowing popular methods worth comparing is difficult.
View Article and Find Full Text PDFAutomatic tool for the reconciliation of serious adverse events for pharmacovigilance: design and implementation of Reconciliaid.
Ther Adv Drug Saf
January 2025
Department of Epidemiology, Biostatistics and Health Data, Centre Antoine Lacassagne, Nice, France.
Background: Reporting serious adverse events (SAEs) is crucial to reduce or avoid toxicities that can lead to major consequences for patient's health due to treatments tested in clinical trials. Its exhaustiveness is often inadequate, and we observe discrepancies between data published by pharmacovigilance organizations and clinical databases.
Objectives: While the process of reconciliation aims at reducing these differences, it remains a very time-consuming and imprecise task.
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