AI Article Synopsis
- Meningeal carcinomatosis is a rare occurrence in gastric cancer, particularly when it manifests without other metastatic sites.
- A 68-year-old man, who previously underwent total gastrectomy for gastric cancer, experienced prolonged high tumor markers and later developed symptoms like hearing loss and facial paralysis, leading to a diagnosis of meningeal carcinomatosis.
- The case highlights the need for awareness of meningeal carcinomatosis as a potential complication in gastric cancer patients, especially when unusual neurological symptoms arise post-surgery.
Article Abstract
Background: Meningeal carcinomatosis is a very rare metastatic site of gastric cancer and meningeal carcinomatosis without other metastatic sites is much extremely rare. Herein, we report our experience with a very rare case of meningeal carcinomatosis which was difficult to diagnose the recurrence by general systemic examination and was found due to the deafness despite the sustained high tumor markers.
Case Presentation: A 68-year-old man consulted a hospital with vomiting and hematemesis. Laboratory tests revealed severe anemia. He was referred to our hospital and underwent an emergency gastroscopy, which revealed Borrman type 3 tumor and oozing of blood. Biopsy specimen showed gastric cancer. After several examinations, total gastrectomy was performed and tegafur-gimeracil-oteracil potassium (S-1) was initiated as adjuvant chemotherapy one month after surgery. Tumor marker levels (CEA and CA19-9) remained high for three months after surgery. S-1 was continued while shortening the imaging study follow-up period. Nine months after surgery, he noticed difficulty in hearing with facial paralysis, dizziness, tinnitus, and appetite loss. He was diagnosed with meningeal carcinomatosis and bilateral internal auditory canal metastasis. He died approximately two months later.
Conclusion: Meningeal carcinomatosis should be considered if bilateral deafness and vestibulopathy develop after gastrectomy, even if no recurrence is apparent in the abdominal cavity.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7683756 | PMC |
| http://dx.doi.org/10.1186/s40792-020-01018-1 | DOI Listing |
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