A new homo-aro-cholestane glycoside parispolyside H, along with nine known compounds, were isolated from 75% ethanolic extract of the rhizome of var. . Their chemical structures were elucidated on the basic of analysis of detailed spectroscopic and physicochemical properties. In addition, the isolated compounds (, -) were evaluated for their cytotoxic activity against HepG2 human liver cancer cell lines. Among them, four known compounds (-) showed cytotoxicity with IC values ranging from 0.41 to 3.6 μM.
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A new homo-aro-cholestane glycoside from the rhizome of var. .
J Asian Nat Prod Res
November 2021
National Engineering Laboratory for Quality Control Technology of Chinese Herbal Medicine, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.
A new homo-aro-cholestane glycoside parispolyside H, along with nine known compounds, were isolated from 75% ethanolic extract of the rhizome of var. . Their chemical structures were elucidated on the basic of analysis of detailed spectroscopic and physicochemical properties.
View Article and Find Full Text PDFHomo-aro-cholestane, furostane and spirostane saponins from the tubers of Ophiopogon japonicus.
Phytochemistry
April 2017
School of Pharmacy and Bioengineering, Chengdu University, Chengdu, 610106, China; Key Laboratory of Mountain Ecological Restoration and Bioresource Utilization and Ecological Restoration Biodiversity Conservation Key Laboratory of Sichuan Province, Chengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041, China. Electronic address:
Phytochemical investigation of the tubers of Ophiopogon japonicus led to the isolation of five previously undescribed steroidal saponins, ophiojaponins A-E, together with twelve known ones. The structures of these isolated compounds were elucidated by detailed spectroscopic analyses and chemical methods. Ophiojaponins A-C are rare naturally occurring C steroidal glycosides possessing a homo-cholestane skeleton with an aromatized ring E.
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