Tetanus is a vaccine-preventable disease that is still endemic in developing countries. We discuss two cases of tetanus in unvaccinated individuals. The first case was a young goat herder who was initially started on benzodiazepine and muscle relaxants. Magnesium sulphate was added later on due to inadequate control after which the patient improved significantly. The second case was an old farmer who was started on magnesium sulphate along with benzodiazepine from the outset. His clinical recovery was faster compared to the first case. We report these cases to discuss the pharmacological options in the management of generalized tetanus with particular reference to magnesium sulphate.
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http://dx.doi.org/10.7759/cureus.11089 | DOI Listing |
Photochem Photobiol
January 2025
Department of Biosciences and Bioengineering, Indian Institute of Technology Bombay, Mumbai, Maharashtra, India.
Virus-laden aerosols play a substantial role in the spread of numerous infectious diseases, particularly in enclosed indoor settings. Ultraviolet-C (UVC) disinfection is known to be a highly efficient method for disinfecting pathogenic airborne viruses. Recent recommendations suggest using far-UVC radiation (222 nm) emitted by KrCl* (krypton-chloride) excimer lamps to disinfect high-risk public spaces due to lower exposure risks than low-pressure (LP) mercury lamps (254 nm).
View Article and Find Full Text PDFAust N Z J Obstet Gynaecol
January 2025
Women and Kids Theme, South Australian Health and Medical Research Institute (SAHMRI), Adelaide, South Australia, Australia.
We assessed the use of magnesium sulphate prior to preterm birth for preventing cerebral palsy in an Australian and New Zealand registry study. Use increased markedly from 32.3% (2012) to 78.
View Article and Find Full Text PDFJ Chromatogr Sci
January 2025
Pesticide Residue Analysis Laboratory, Department of Entomology, Punjab Agricultural University, Ludhiana 141004, Punjab, India.
Validation of Quick, Easy, Cheap, Effective, Rugged, and Safe (QuEChERS) method was performed for estimation of imidacloprid (IM) and its metabolites in maize leaves, immature kernels, mature kernels, stalk, and soil using liquid chromatograph tandem mass spectrometry, coupled with electrospray ionization. The extraction in different matrices of maize and soil was performed using acetonitrile +0.1% formic acid followed by clean-up with primary secondary amine sorbent and anhydrous magnesium sulfate.
View Article and Find Full Text PDFSci Rep
January 2025
Department of Pediatrics, Faculty of Medicine, Oita University, 1-1 Idaigaoka, Hasama, Yufu, Oita, 879-5593, Japan.
In the management of pregnancy, ritodrine has been used to prevent preterm birth, and magnesium sulfate (MgSO) has been used to prevent preterm labor and preeclampsia. Neonates born to mothers receiving these medications occasionally show an increase in serum potassium concentration. Recently, an elevated risk of neonatal hyperkalemia has been reported, particularly when ritodrine and MgSO are co-administered; however, the underlying mechanisms remain unclear.
View Article and Find Full Text PDFSci Rep
January 2025
Intensive Care Medicine, Heyou Hospital, Foshan, 528306, Guangdong, China.
Heart failure with preserved ejection fraction (HFpEF) emerges as a singular subclass of heart failure, bereft of specific therapeutic options. Magnesium, an indispensable trace element, is essential to the preservation of cardiac integrity. However, the association between magnesium supplementation and mortality in HFpEF patients remains unclear.
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