A new squalene derivative from L. (Solanaceae).

Nat Prod Res

Department of Chemistry, University of Ibadan, Ibadan, Nigeria.

Published: April 2022

is an annual herb which has tremendous medicinal uses. The antioxidant activity of the whole plant extract of was investigated using DPPH radical scavenging activity. Purified compounds were isolated using column chromatography method. Their structures were determined using various spectroscopic techniques. A new compound named as Squalen-1-ol, Phytol, squalene and α-tocopherol were isolated. These compounds were isolated for the first time from The extract of gave a significant IC value of 0.77 mg/mL as compared with the standard ascorbic acid with IC value of 0.24 mg/mL. It can be correlated that the antioxidant activity of could be attributed to the presence of α - tocopherol which is a known antioxidant. The presence of these compounds gives a further added pharmacological value to the plant.

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Source
http://dx.doi.org/10.1080/14786419.2020.1844691DOI Listing

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