AI Article Synopsis
- The study investigates the effectiveness of different microbiological culture methods for diagnosing prosthetic joint infections, focusing on the challenges of low sensitivity in standard cultures.
- It compares conventional culture techniques with the use of enrichment broth and BacT/ALERT pediatric blood culture bottles across 121 specimens from 44 patients.
- Results show that pediatric bottles provide faster detection and higher sensitivity compared to solid media alone, suggesting that their combined use with solid media is more effective for diagnosing these infections.
Article Abstract
The diagnosis of prosthetic joint infections and isolation of causative microorganisms has been found to be challenging in microbiology laboratories due to low sensitivity of microbiological culture. The aim of this study was to compare the use of conventional culture methods with the use of both enrichment broth and BacT/ALERT paediatric blood culture bottles, for the diagnosis of prosthetic joint infections. A total of 121 specimens from 44 patients were processed using three methods of microbiological culture: solid media, enrichment broth and paediatric bottles. The paediatric bottle method had a significantly lower (p<0.0001) time to detection than the standard solid media method, and was significantly more sensitive than solid media when used independently (93.33%, CI 83.27-98.09, vs 60.00%, CI 45.43-73.33). The combination use of solid media with paediatric bottles was found to be superior to the conventional solid media method and combination use with enrichment broth.
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| http://dx.doi.org/10.1016/j.pathol.2020.08.015 | DOI Listing |
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