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Cetyltrimethylammonium Chloride (CTAC) and Its Formulated Mouthwash Reduce the Infectivity of Streptococcus mutans and Candida albicans in Mono and Dual State.
Appl Biochem Biotechnol
December 2024
Department of Biotechnology, Science Campus, Alagappa University, Karaikudi, India.
Early childhood caries (ECC), a severe form of dental caries, is exacerbated by the synergistic interaction between Streptococcus mutans and Candida albicans, leading to greater disease severity than their individual effects. This underscores the need for more targeted and potent therapeutic alternatives. Given the promising anti-infective properties of quaternary ammonium surfactants (QAS), this study explores the microbicidal properties of one such QAS, cetyltrimethylammonium chloride (CTAC), against both individual- and dual-species cultures of S.
View Article and Find Full Text PDFChallenges for the Implementation of Primary Standard Dosimetry in Proton Minibeam Radiation Therapy.
Cancers (Basel)
November 2024
Radiotherapy and Radiation Dosimetry, National Physical Laboratory, Teddington TW11 0LW, UK.
Article Synopsis
- Spatial fractionation of proton fields in cancer treatment improves sparing of healthy tissue while ensuring tumor control.
- This study demonstrated the use of the National Physical Laboratory's Primary Standard Proton Calorimeter to measure absorbed dose in a proton beam with a specific configuration.
- Results indicated that uncertainty in absorbed dose measurements was mainly due to positioning accuracy, suggesting that reference dosimetry should focus on measuring Dose-Area Product or using SOBP for more reliable outcomes in spatially fractionated fields.
Histidine-rich protein (hrp) 2-based RDT false-negatives and Plasmodium falciparum hrp 2 and 3 gene deletions in low, seasonal and intense perennial transmission zones in Cameroon: a cross - sectional study.
BMC Infect Dis
September 2024
Medical Research Council Unit, The Gambia at London School of Hygiene and Tropical Medicine, Fajara, The Gambia.
Background: False negative rapid diagnostic tests (RDTs) accruing to the non-detection of Plasmodium falciparum histidine-rich protein 2/3 (Pfhrp2/3) is threatening the diagnosis and management of malaria. Although regular monitoring is necessary to gauge the level of efficacy of the tool, studies in Cameroon remain limited. This study assessed Plasmodium spp.
View Article and Find Full Text PDFArticle Synopsis
- Researchers studied strokes from 1990 to 2021 to understand how many people get them and how they are affected around the world.
- In 2021, strokes caused about 7.3 million deaths and were a major cause of health problems, especially in specific regions like Southeast Asia and Oceania.
- There are differences in stroke risks based on where people live and their age, and some areas actually saw more strokes happening since 2015.
Impact of Skin Care Products on Phthalates and Phthalate Replacements in Children: the ECHO-FGS.
Environ Health Perspect
September 2024
Department of Public Health Sciences, Medical University of South Carolina, Charleston, South Carolina, USA.
Background: Phthalates and their replacements have been implicated as developmental toxicants. Young children may be exposed to phthalates/replacements when using skin care products (SCPs).
Objectives: Our objective is to assess the associations between use of SCPs and children's urinary phthalate/replacement metabolite concentrations.
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