AI Article Synopsis

  • The study investigates the connection between balance disorders (BDs), like vertigo, and the risk of strokes (acute cerebrovascular accidents, ACAs), highlighting that existing research has limitations.
  • The research involved tracking nearly 8,000 participants over two years to analyze how various cardiovascular risk factors (CVRFs) relate to BDs and ACAs, using both univariate and multivariate analysis methods.
  • Findings suggest that while BDs are associated with a higher risk of ACAs, they likely act as confounding factors linked to other CVRFs, serving as indicators for identifying individuals at increased risk for strokes.

Article Abstract

Purpose: There is a higher risk of stroke after suffering from balance disorders (BDs) such as vertigo or dizziness. The causal relationship remains unclear due to the limited scope of the existing studies and the high prevalence of cardiovascular risk factors (CVRFs) in BD patients. The objective of this study is to clarify the role that BDs seem to have in the development of acute cerebrovascular accidents (ACAs).

Methods: This is an observational prospective study. The CVRFs and demographic factors of a sample of our population were noted. Five clusters of patients were tracked over the course of 2 years to detect and diagnose BDs and ACAs. The causal relationships between the CVRFs, BDs and ACAs were analyzed in a univariate analysis. A logistic regression multivariant analysis was performed on those variables that reached statistical significance.

Results: The sample included 7886 participants and 31 ACAs were recorded. CVRFs that reached statistical significance included age ≥ 60, hypertension, diabetes mellitus, dyslipidemia, ischemic heart disease, atrial fibrillation and previous ACAs. The relationship between BDs and ACAs always reached statistical significance, regardless of how the BD variable was defined. Five different multivariate analyses were performed, but in none of them did the BD variables significantly reduce the deviance and thus, they were not taken into account when building the final model.

Conclusion: This study shows that BDs are probably confounders that are closely linked to other CVRFs and they are also useful red flags to identify patients at a higher risk of suffering from ACAs.

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Source
http://dx.doi.org/10.1007/s00405-020-06465-yDOI Listing

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