AI Article Synopsis
- The study by Ryder et al. (2020) highlights the role of fragile-X mental retardation protein in regulating the movement of cen mRNA in Drosophila.
- Improper localization of cen mRNA affects cell division and development, suggesting its critical role in ensuring correct mitotic processes.
- The research emphasizes the functional significance of mRNA positioning at centrosomes for maintaining proper cell function and development.
Article Abstract
The functional importance of mRNA localization to centrosomes is unclear. Ryder et al. (2020. J. Cell Biol. https://doi.org/10.1083/jcb.202004101) identify fragile-X mental retardation protein as a regulator of centrocortin (cen) mRNA dynamics in Drosophila. Mistargeting of cen impairs division and development, indicating that cen mRNA localization to centrosomes ensures mitotic fidelity.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7716381 | PMC |
| http://dx.doi.org/10.1083/jcb.202010172 | DOI Listing |
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