Objectives: Describe an augmented intelligence approach to facilitate the update of evidence for associations in knowledge graphs.
Methods: New publications are filtered through multiple machine learning study classifiers, and filtered publications are combined with articles already included as evidence in the knowledge graph. The corpus is then subjected to named entity recognition, semantic dictionary mapping, term vector space modeling, pairwise similarity, and focal entity match to identify highly related publications. Subject matter experts review recommended articles to assess inclusion in the knowledge graph; discrepancies are resolved by consensus.
Results: Study classifiers achieved F-scores from 0.88 to 0.94, and similarity thresholds for each study type were determined by experimentation. Our approach reduces human literature review load by 99%, and over the past 12 months, 41% of recommendations were accepted to update the knowledge graph.
Conclusion: Integrated search and recommendation exploiting current evidence in a knowledge graph is useful for reducing human cognition load.
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http://dx.doi.org/10.1093/jamiaopen/ooaa028 | DOI Listing |
Sci Rep
January 2025
Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Patients with Moyamoya disease (MMD) exhibit significant alterations in brain structure and function, but knowledge regarding gray matter networks is limited. The study enrolled 136 MMD patients and 99 healthy controls (HCs). Clinical characteristics and gray matter network topology were analyzed.
View Article and Find Full Text PDFBioinformatics
January 2025
Department of Computational Biomedicine, Center for Artificial Intelligence Research and Education, Cedars Sinai Medical Center, 700 N. San Vicente Blvd., Pacific Design Center, Suite G-541H, West Hollywood, 90069, CA, USA.
Motivation: LLMs like GPT-4, despite their advancements, often produce hallucinations and struggle with integrating external knowledge effectively. While Retrieval-Augmented Generation (RAG) attempts to address this by incorporating external information, it faces significant challenges such as context length limitations and imprecise vector similarity search. ESCARGOT aims to overcome these issues by combining LLMs with a dynamic Graph of Thoughts and biomedical knowledge graphs, improving output reliability and reducing hallucinations.
View Article and Find Full Text PDFDatabase (Oxford)
January 2025
Environmental Genomics and Systems Biology, Lawrence Berkeley National Laboratory, One Cyclotron Rd., Berkeley, CA 94720, United States.
Ontologies and knowledge graphs (KGs) are general-purpose computable representations of some domain, such as human anatomy, and are frequently a crucial part of modern information systems. Most of these structures change over time, incorporating new knowledge or information that was previously missing. Managing these changes is a challenge, both in terms of communicating changes to users and providing mechanisms to make it easier for multiple stakeholders to contribute.
View Article and Find Full Text PDFGlob Chang Biol
January 2025
Key Laboratory of Agro-Ecological Processes in Subtropical Region, Institute of Subtropical Agriculture, Chinese Academy of Sciences, Changsha, China.
Unraveling how agricultural management practices affect soil biota network complexity and stability and how these changes relate to soil processes and functions is critical for the development of sustainable agriculture. However, our understanding of these knowledge still remains unclear. Here, we explored the effects of soil management intensity on soil biota network complexity, stability, and soil multifunctionality, as well as the relationships among these factors.
View Article and Find Full Text PDFFront Pharmacol
January 2025
Department of Pharmacy, The Fourth Hospital of Hebei Medical University, Shijiazhuang, China.
Introduction: Pharmacists are increasingly adopting patient-centered roles, improving healthcare outcomes by reducing medication errors and costs. In China, recent healthcare reforms recognize and compensate for pharmacy services. However, patient awareness of these services and their willingness to pay (WTP) remain underexplored.
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