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Inflammatory Bowel Disease in the Older Adult. | LitMetric

Inflammatory Bowel Disease in the Older Adult.

Clin Geriatr Med

Inflammatory Bowel Disease Program, VA Ann Arbor Healthcare System, VA Center for Clinical Management Research, 2215 Fuller Road, Ann Arbor, MI 48105, USA; Division of Gastroenterology & Hepatology, Department of Internal Medicine, Michigan Medicine, 3912 Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA; Institute for Healthcare Policy and Innovation, University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA; Michigan Integrated Center for Health Analytics and Medical Prediction (MiCHAMP), University of Michigan, 2800 Plymouth Road, Ann Arbor, MI 48109, USA. Electronic address: https://twitter.com/AkbarWaljee.

Published: February 2021

AI Article Synopsis

  • - Treatment of inflammatory bowel disease (IBD) in older adults poses challenges due to specific age-related characteristics that can complicate management.
  • - New medical treatments for IBD emphasize not only symptom control but also prevention of disease progression, necessitating careful consideration of their safety for elderly patients.
  • - Older patients often deal with comorbidities, polypharmacy, and altered drug metabolism, which elevate the risk of complications and adverse drug interactions during treatment.

Article Abstract

Although management of inflammatory bowel disease follows a similar approach for all adults, there are certain characteristics making its treatment more challenging in older patients. The advent of novel medical treatments has changed the paradigm of inflammatory bowel disease, with an increasing focus on preventing disease progression in addition to controlling symptoms. The safety of these therapies in the elderly needs to be considered. Management of inflammatory bowel disease in the elderly is confounded by comorbidities that can increase the risk of medication or surgical complications; polypharmacy and altered pharmacokinetics also increase the risk of drug-drug interactions and adverse events.

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Source
http://dx.doi.org/10.1016/j.cger.2020.08.013DOI Listing

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