AI Article Synopsis
- - The study aimed to improve the detection of superficial squamous cell carcinoma (SCC) in the esophagus using virtual chromoendoscopy by evaluating the impact of different air volumes during endoscopy.
- - Researchers analyzed 101 cases of flat type esophageal SCC and compared the visibility of the lesions under less-air versus standard-air conditions using narrow band imaging (NBI).
- - Results indicated that visibility of SCC was significantly better with less-air conditions, with up to 67% of lesions showing improved visibility, suggesting that using less air could enhance detection during endoscopic exams.
Article Abstract
Background: The current virtual chromoendoscopy equipment cannot completely detect superficial squamous cell carcinoma (SCC) in the esophagus, despite its development in the recent years. Thus, in this study, we aimed to elucidate the appropriate air volume during endoscopic observation to improve the visibility of esophageal SCC.
Methods: This retrospective study included a total of 101 flat type esophageal SCCs identified between April 2017 and January 2019 at the Department of Gastrointestinal Oncology, Osaka International Cancer Institute. Video images of narrow band imaging (NBI) under both less-air and standard-air conditions were recorded digitally. Videos were evaluated by five endoscopists. Relative visibility between less-air and standard-air conditions of the brownish area, brownish color change of the epithelium, and dilated intrapapillary capillary loop (IPCL) were graded as 5 (definitely better under less-air condition) to 1 (definitely worse under less-air condition), with 3 indicating average visibility (equivalent to standard-air observation).
Results: The mean (standard deviation) visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs under less-air condition were 3.94 (0.58), 3.73 (0.57), and 4.13 (0.60), respectively, which were significantly better than that under standard-air condition (p < 0.0001). Esophageal SCC evaluated as ≥ 4 in the mean visibility score of the brownish area, brownish color change of the epithelium, and dilated IPCLs accounted for 50% (51/101 lesions), 34% (34/101 lesions), and 67% (68/101 lesions), respectively.
Conclusions: The present results suggested that NBI with less air might improve the visibility of flat type esophageal SCC compared with NBI with standard air. Less-air NBI observation may facilitate the detection of flat type esophageal SCC.
Trial Registration: The present study is a non-intervention trial.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7678292 | PMC |
| http://dx.doi.org/10.1186/s12876-020-01534-2 | DOI Listing |
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