Female genital tuberculosis is an important cause of infertility in developing countries where tuberculosis is endemic. However, the true incidence of genital tuberculosis is unknown because symptoms and signs are usually minimal, making its detection difficult. We herein report a case of subfertility due to endometrial tuberculosis. The patient had primary infertility and planned to utilize assisted reproductive technology because of bilateral fallopian tube obstruction. She underwent hysteroscopy and endometrial biopsy. The biopsy revealed epithelioid cells and multinuclear giant cells in the interstitium, and tuberculosis of the endometrium could not be excluded. Chest computed tomography showed secondary pulmonary tuberculosis in the upper left lung. A tuberculin test was positive, and a sputum culture of was negative. The clinical diagnosis was secondary pulmonary tuberculosis. Considering the above findings in combination with the endometrial biopsy results, we concluded that the patient had endometrial tuberculosis. She underwent antituberculosis treatment for 6 months, after which the endometrial tuberculosis resolved and she achieved pregnancy by in vitro fertilization.
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http://dx.doi.org/10.1177/0300060520967824 | DOI Listing |
Int J Surg Case Rep
December 2024
Lung Transplantation Research Center, National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Electronic address:
Trop Doct
September 2024
Senior Consultant, Pulmonology, Critical Care & Sleep Medicine, National Heart Institute, New Delhi, India.
Female genital tuberculosis (FGTB) is asymptomatic or may present with a few symptoms among which infertility is the most common. The diagnosis of FGTB is challenging, as there is no single diagnostic test available.We researched 50 infertile patients by various special investigations and found 50% had tuberculosis, by various means.
View Article and Find Full Text PDFBackground: Endometrial Tuberculosis is one of the most common gynecological problems known to have serious implications for the quality of life like infertility. The commonly practiced histopathology solely relies on the suggestive feature of Tuberculosis (TB) with low specificity. Regarding the alternative bacteriological and molecular detection tools, little evidence was generated on their utility in the diagnosis of endometrial tuberculosis in Ethiopia.
View Article and Find Full Text PDFBMJ Case Rep
August 2024
Division of Infectious Disease, Albert Einstein College of Medicine, Bronx, NY, USA.
AJOG Glob Rep
August 2024
LifeCell International (P) Ltd. (Nandagopal, Rajan N., Padhiar, Abhaya, and Ghambir), Chennai, Tamil Nadu, India.
Background: This study aimed to assess the utility of real-time-polymerase chain reaction (PCR) for diagnosing chronic endometritis (CE) by targeting 11 prevalent pathogens and to compare the outcomes with conventional culture-based diagnosis.
Study Design: A retrospective analysis was conducted on 500 patients with clinical conditions such as abnormal bleeding, in vitro fertilization failure, recurrent implantation failure, recurrent miscarriage, and recurrent pregnancy loss. The prevalence of 11 key pathogens associated with CE was evaluated in endometrial biopsy samples.
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