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PGT-A: what's it for, what's wrong?
J Assist Reprod Genet
January 2025
Department of Obstetrics and Gynecology, Cairo University, Cairo, Egypt.
PGT-A, what's it for? Considering the increase in fetal aneuploidies with a woman's age and the high number of miscarriages associated with fetal karyotype anomalies, the concept of selecting IVF embryos based on their karyotype in order to transfer only euploid embryos and eliminate aneuploid ones was proposed. Preimplantation genetic testing for aneuploidy (PGT-A) was then established, nearly 30 years ago, with the expectation that the transfer of euploid embryos would lead to a significant improvement in medically assisted reproduction (MAR) outcomes. PGT-A, what's wrong? Despite the practice and widespread use, PGT-A has not consistently proven its effectiveness.
View Article and Find Full Text PDFEvaluation of the prediagnosis and management of ChatGPT-4.0 in clinical cases in cardiology.
Future Cardiol
March 2024
Department of Cardiology, Kütahya Evliya Çelebi Training & Research Hospital, Kütahya, 43000, Turkey.
Evaluation of the performance of ChatGPT-4.0 in providing prediagnosis and treatment plans for cardiac clinical cases by expert cardiologists. 20 cardiology clinical cases developed by experienced cardiologists were divided into two groups according to preparation methods.
View Article and Find Full Text PDFAconite-Induced Metamorphosis From Beauty to Ugliness in a Japanese Tale.
J Craniofac Surg
July 2024
Department of Plastic Surgery, Daejeon Eulji Medical Center, Eulji University, Daejeon.
The authors present a narrative that details the cause and process of a woman's transformation from beauty to ugliness in a Japanese tale. In " Tokaido Yotsuya Kaidan ," the metamorphosis from a beauty to an ugly woman is analyzed. After taking medication to recover from childbirth, Oiwa's face became disfigured and grotesque.
View Article and Find Full Text PDFViews of patients with progressive illness and carers about the role of digital advance care planning systems to record and share information: A qualitative study.
Palliat Med
July 2024
Cicely Saunders Institute of Palliative Care, Policy & Rehabilitation, King's College London, London, UK.
Background: Digital approaches are being explored internationally to support the elicitation, documentation and sharing of advance care planning information. However, the views and experiences of patients and carers are little understood, impeding the development and impact of digital approaches to strengthen palliative and end-of-life care.
Aim: To explore perspectives of patients with progressive illness and their carers on digital approaches to advance care planning, anticipated impact from their use and expectations for their future development.
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