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Oropharyngeal Lymphogranuloma Venereum: A Clinical Reasoning Challenge and Literature Review.
J Community Hosp Intern Med Perspect
January 2025
Internal Medicine Residency Program, Florida State University College of Medicine, Tallahassee, FL, USA.
Lymphogranuloma venereum (LGV) is a sexually transmitted infection typically caused by serovars L1-L3 of . These serovars are tissue-invasive with a preponderance for lymphatic spread and can be acquired via unprotected oral, anal, or vaginal sex. We present the case of a 23-year-old with a prior history of syphilis admitted with four weeks of progressively enlarging painful right cervical lymphadenopathy.
View Article and Find Full Text PDFSeparating Infectious Proctitis from Inflammatory Bowel Disease-A Common Clinical Conundrum.
Microorganisms
November 2024
Department of Gastroenterology, St George's University Hospital, London SW17 0QT, UK.
Proctitis refers to inflammation in the rectum and may result in rectal bleeding, discharge, urgency, tenesmus, and lower abdominal pain. It is a common presentation, particularly in genitourinary medicine and gastroenterology, as the two most common causes are sexually transmitted infections and inflammatory bowel disease. The incidence of infective proctitis is rising, particularly amongst high-risk groups, including men who have sex with men, those with HIV seropositive status, and those participating in high-risk sexual behaviours.
View Article and Find Full Text PDFLymphogranuloma Venereum Surveillance in Chlamydia trachomatis Positive Male Rectal Swabs Collected from I Want The Kit in Maryland, United States.
Sex Transm Dis
December 2024
Division of Infectious Diseases, Johns Hopkins University, Baltimore, Maryland.
Background: Infection with Chlamydia trachomatis (CT) can have distinct clinical presentations, such as trachoma, or lymphogranuloma venereum (LGV). Certain populations are at greater risk for LGV acquisition and transmission, which requires a longer duration of therapy than other urogenital CT sexually transmitted infections (STIs). Commercial assays are not available in the United States to distinguish LGV from non-LGV serovars.
View Article and Find Full Text PDFThe challenges in lymphogranuloma venereum diagnosis whether NAAT is negative, a case series.
Int J STD AIDS
December 2024
Internal Medicine and infectious Diseases Department, UZ Brussel, Vije Universiteit Brussel (VUB), Brussel, Belgium.
Article Synopsis
- Persistent inguinal lymphadenopathy can be caused by various conditions, including the sexually transmitted infection lymphogranuloma venereum (LGV), which may be overlooked due to diagnostic challenges.
- Two male patients with a high risk for STIs presented with inguinal lymphadenopathy; initial tests were negative, leading to prolonged diagnostic delays before confirming LGV.
- Both patients improved significantly after treatment with doxycycline, highlighting the importance of considering LGV in similar cases of persistent lymphadenopathy.
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