Covid-19 pandemic severely affected human health worldwide. Till October 19, 2020, total confirmed patients of COVID-19 are 39,944,882, whereas 1,111,998 people died across the globe. Till to date, we do not have any specific medicine and/or vaccine to treat COVID-19; however, research is still going on at war footing. So far vaccine development is concerned, here it is noteworthy that till now three major variants (named A, B, and C) of severe acute respiratory syndrome-coronavirus2 (SARS-CoV-2) have been recognized. Increased mutational rate and formation of new viral variants may increase the attrition rate of vaccines and/or candidate chemotherapies. Herbal remedies are chemical cocktails, thus open another avenue for effective antiviral therapeutics development. In fact, India is a large country, which is densely populated, but the overall severity of COVID-19 per million populations is lesser than any other country of the world. One of the major reasons for the aforesaid difference is the use of herbal remedies by the Government of India as a preventive measure for COVID-19. Therefore, the present review focuses on the epidemiology and molecular pathogenesis of COVID-19 and explores algal metabolites for their antiviral properties.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7753317 | PMC |
| http://dx.doi.org/10.1002/ptr.6948 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
How does the coral microbiome mediate its natural host fitness under climate stress conditions? Physiological, molecular, and biochemical mechanisms.
Mar Environ Res
December 2024
Pharmacognosy Department, College of Pharmacy, Cairo University, Kasr El-Aini St., Cairo, P.B, 11562, Egypt. Electronic address:
Although the symbiotic partnership between corals and algal endosymbionts has been extensively explored, interactions between corals, their algal endosymbionts and microbial associates are still less understood. Screening the response of natural microbial consortiums inside corals can aid in exploiting them as markers for dysbiosis interactions inside the coral holobiont. The coral microbiome includes archaea, bacteria, fungi, and viruses hypothesized to play a pivotal vital role in coral health and tolerance to heat stress condition via different physiological, biochemical, and molecular mechanisms.
View Article and Find Full Text PDFLesser-Known Cyanotoxins: A Comprehensive Review of Their Health and Environmental Impacts.
Toxins (Basel)
December 2024
Faculty of Medicine and Medical Sciences, University of Balamand, Kalhat, Tripoli P.O. Box 100, Lebanon.
Cyanobacteria, also known as blue-green algae, are a diverse phylum of photosynthetic, Gram-negative bacteria and one of the largest microbial taxa. These organisms produce cyanotoxins, which are secondary metabolites that can have significant impacts on both human health and the environment. While toxins like Microcystins and Cylindrospermopsins are well-documented and have been extensively studied, other cyanotoxins, including those produced by and , remain underexplored.
View Article and Find Full Text PDFImpact of Ultrasound- and Microwave-Assisted Extraction on Bioactive Compounds and Biological Activities of and .
Mar Drugs
November 2024
Nuclear Research Centre of Birine, Ain Oussera 17200, Algeria.
This study represents the first investigation into the ultrasonic and microwave extraction of bioactive metabolites from (red seaweed) and () (brown seaweed), with a focus on their biological activities. The research compares ultrasound-assisted extraction (UAE) with microwave-assisted extraction (MAE) utilizing a hydromethanolic solvent to evaluate their effects on these seaweeds' bioactive compounds and biological activities. The assessment included a series of antioxidant essays: DPPH, ABTS, phenanthroline, and total antioxidant capacity, followed by enzyme inhibition activities: alpha-amylase and urease.
View Article and Find Full Text PDFApplications of low-temperature plasma technology in microalgae cultivation and mutant breeding: A comprehensive review.
Bioresour Technol
December 2024
CAS Key Laboratory of High Magnetic Field and Iron Beam Physical Biology, Institute of Intelligent Machines, Hefei Institute of Physical Sciences, Chinese Academy of Sciences, Hefei 230031, China; Science Island Branch of Graduate School, University of Science and Technology of China, Hefei 230026, China. Electronic address:
Low-temperature plasma (LTP) has gained significant attention recently due to its unique properties and potentially wide applications in agriculture, medicine, and food industry. Microalgae have become important to human life since they provide raw materials and bioactive products to industries. This review especially examines how LTP technology can be utilized to enhance microalgae growth and production of various metabolites and bioactive compounds such as astaxanthin, biofuel, lipid, proteins, and polysaccharides through mutagenesis and/or stimulation.
View Article and Find Full Text PDFShear stress controls prokaryotic and eukaryotic biofilm communities together with EPS and metabolomic expression in a semi-controlled coastal environment in the NW Mediterranean Sea.
Environ Microbiome
December 2024
Laboratoire MAPIEM, Université de Toulon, Toulon, France.
While waves, swells and currents are important drivers of the ocean, their specific influence on the biocolonization of marine surfaces has been little studied. The aim of this study was to determine how hydrodynamics influence the dynamics of microbial communities, metabolic production, macrofoulers and the associated vagile fauna. Using a field device simulating a shear stress gradient, a multi-scale characterization of attached communities (metabarcoding, LC-MS, biochemical tests, microscopy) was carried out for one month each season in Toulon Bay (northwestern Mediterranean).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!