Resistance to pyrethroids (PY) and organophosphate (OP) insecticides is widespread among populations of Culex quinquefasciatus, the major vector of lymphatic filariasis (LF). The present study was designed to detect the L1014F kdr (knockdown resistant) mutation among Cx. quinquefasciatus populations in the filarial belt of Sri Lanka. Mosquitoes were reared from field-caught larvae from seven localities where LF is endemic. Susceptibility status of Cx. quinquefasciatus to adulticides, 0.05% deltamethrin, 0.75% permethrin, 5% malathion, and the larvicide temephos was determined using the standard WHO susceptibility tests. A fragment of vgsc gene was amplified and sequenced to identify the responsible kdr mutations. The susceptibility test results revealed less than 90% mortalities for 0.05% deltamethrin, and 0.75% permethrin and temephos. For 5% malathion, all study sites except Maharagama revealed greater than 90% mortality. The L1014F kdr mutation was observed in all studied populations. Although the overall microfilaria rate is less than 1% in the country, there is a high risk of re-emergence of LF in Sri Lanka due to abundant Cx. quinquefasciatus mosquitoes, increased resistant status to currently used insecticides, imported LF cases, higher rates of microfilaria among neighboring countries, and the advancement of tourism.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1111/jvec.12391 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Autoencoder based data clustering for identifying anomalous repetitive hand movements, and behavioral transition patterns in children.
Phys Eng Sci Med
January 2025
Institute of Digital Technologies for Personalized Healthcare (MeDiTech), University of Applied Sciences and Arts of Southern Switzerland, Via Pobiette, Manno, 6928, Manno, Switzerland.
The analysis of repetitive hand movements and behavioral transition patterns holds particular significance in detecting atypical behaviors in early child development. Early recognition of these behaviors holds immense promise for timely interventions, which can profoundly impact a child's well-being and future prospects. However, the scarcity of specialized medical professionals and limited facilities has made detecting these behaviors and unique patterns challenging using traditional manual methods.
View Article and Find Full Text PDFLeveraging Underutilized Sri Lankan Fruits in the Fight against Autoimmune Disorders.
Antiinflamm Antiallergy Agents Med Chem
January 2025
Institute for Combinatorial Advanced Research and Education, General Sir John Kotelawala Defence University, Ratmalana, Sri Lanka.
The potential of underutilized plant species to improve food security, health, eco-nomic output, and the environment has not been fully realized. Sri Lanka an island on the Indian Ocean is home to numerous plant species with significant medicinal potential, in-cluding many underutilized plants that could help meet the growing demand for food, en-ergy, medicines, and industrial resources. Globally, there are over a thousand known and unknown phytochemicals derived from plants.
View Article and Find Full Text PDFThe influence of social interactions in mitigating psychological distress during the COVID-19 pandemic: a study in Sri Lanka.
Front Psychol
January 2025
Cardiff University, Cardiff, United Kingdom.
Massive changes in many aspects related to social groups of different socioeconomic backgrounds were caused by the COVID-19 pandemic and as a result, the overall state of mental health was severely affected globally. This study examined how the pandemic affected Sri Lankan citizens representing a range of socioeconomic backgrounds in terms of their mental health. The data used in this research was gathered from 3,020 households using a nationwide face-to-face survey, from which a processed dataset of 921 responses was considered for the final analysis.
View Article and Find Full Text PDFPerspectives of Midwives and Nurse Practitioners in Kentucky on Exercise Counseling During Pregnancy: A Qualitative Study.
SAGE Open Nurs
January 2025
Exercise Science, Western Kentucky University, Bowling Green, KY, USA.
Introduction: Healthcare professionals are in an optimal position to deliver exercise information to pregnant women, yet previous research suggests this seldom happens. Midwives and nurse practitioners, who may have more time with pregnant women, are particularly well suited for this role.
Objectives: This qualitative study examined the exercise advice and counseling provided by midwives and nurse practitioners in Kentucky, focusing on the barriers they face.
Global distribution and sustainable management of Asian corn borer (ACB), (Lepidoptera: Crambidae): recent advancement and future prospects.
Bull Entomol Res
January 2025
College of Plant Protection, Jilin Agricultural University, Changchun, P.R. China.
The Asian corn borer (ACB), (Guenée, 1854), is a serious pest of several crops, particularly a destructive pest of maize and other cereals throughout most of Asia, including China, the Philippines, Indonesia, Malaysia, Thailand, Sri Lanka, India, Bangladesh, Japan, Korea, Vietnam, Laos, Myanmar, Afghanistan, Pakistan and Cambodia. It has long been known as a pest in South-east Asia and has invaded other parts of Asia, Solomon Islands, parts of Africa and certain regions of Australia and Russia. Consequently, worldwide efforts have been increased to ensure new control strategies for management.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!