AI Article Synopsis
- * A pilot study tested a new cream containing 12% hydroquinone, 6% kojic acid, and 5% vitamin C on 6 women with melasma, using a scoring system to measure its efficacy.
- * Results showed a significant average reduction of about 63.77% in melasma severity, suggesting that this combination treatment could be a promising option, though more research is needed.
Article Abstract
Background: Melasma is a common hyperpigmentation disorder with numerous, but often unsatisfactory treatment options.
Aims: A pilot study to evaluate the efficacy and safety of a novel topical combination of 12% hydroquinone, 6% kojic acid, and 5% vitamin C cream for melasma.
Patients And Methods: A pilot study of 6 women with melasma was conducted at an academic dermatology department and a private dermatology practice to evaluate the efficacy of a topical combination of 12% hydroquinone, 6% kojic acid, and 5% vitamin C cream, entitled the "Tam Formula." Two blinded evaluators calculated Melasma Area and Severity Index (MASI) Scores before and after treatment to evaluate change from baseline, and statistical analysis was performed.
Results: Treatment with this combination topical cream resulted in an average 63.77 ± 22.10 percent reduction in MASI scores.
Conclusions: While there is a need for further investigation, this pilot study indicates the Tam Formula may provide an alternative treatment option for melasma.
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| http://dx.doi.org/10.1111/jocd.13849 | DOI Listing |
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