The increasing evidence has made it necessary to change international recommendations for the diagnosis and treatment of resistant tuberculosis repeatedly in the recent years. This year, the WHO has published comprehensive recommendations that take into account these developments. The current German tuberculosis guideline was published in 2017 with differing recommendations in some areas. Here the new WHO recommendations of 2020 for rapid diagnosis and therapy of resistant tuberculosis are summarized and the relevant differences are commented for Germany, Austria and Switzerland. A complete re-evaluation of the literature is currently taking place by updating the German-language AWMF 2k guidelines.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1055/a-1266-5207 | DOI Listing |
Lab Chip
January 2025
Laboratory for Electrical Instrumentation and Embedded Systems, IMTEK - Department of Microsystems Engineering, University of Freiburg, Georges-Köhler-Allee 103, 79110 Freiburg, Germany.
Cell cultures, organs-on-chip and microphysiological systems become increasingly relevant as models, , in drug development, disease modelling, toxicology or cancer research. It has been underlined repeatedly that culture conditions and metabolic cues have a strong or even essential influence on the reproducibility and validity of such experiments but are often not appropriately measured or controlled. Here we review microsensor systems for cell metabolism for the continuous measurement of culture conditions in microfluidic and lab-on-chip platforms.
View Article and Find Full Text PDFPaediatr Drugs
January 2025
Department of Development and Regeneration, KU Leuven, Herestraat 49, 3000, Leuven, Belgium.
PLoS Biol
January 2025
Research Group Meiotic Recombination and Genome Instability, Max Planck Institute for Evolutionary Biology, Plön, Germany.
A recent study in PLOS Biology on the epigenetic recombination regulator PRDM9 in salmonid fish reveals that its function has been preserved across vertebrates for hundreds of millions of years, with rapidly evolving DNA-binding domains being a defining attribute.
View Article and Find Full Text PDFEur Urol
January 2025
Division of Oncology, Unit of Urology, IRCCS Ospedale San Raffaele, Vita-Salute San Raffaele University, Milan, Italy.
Peer review and comments from reviewers are part of the submission process for scientific papers. We provide tips on how best to respond to reviewers, and point out the most common mistakes that authors make. The ultimate goal is to work with reviewers and editors to improve the quality of a paper so that it is accepted for publication.
View Article and Find Full Text PDFNatl Sci Rev
December 2024
State Key Laboratory of Lithospheric and Environmental Co-evolution, University of Science and Technology of China, China.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!