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Perihematomal oligemia is associated with progression to ischemia and poor outcome in a subset of patients with intracerebral hemorrhage.
Eur Radiol
December 2024
Department of Neurological and Vision Sciences, Neurology Unit, ASST Spedali Civili, Brescia, Italy.
Article Synopsis
- The study aimed to explore how perihematomal oligemia changes over time in patients with acute intracerebral hemorrhage (ICH), which is bleeding within the brain.
- Researchers analyzed data from 150 patients by using imaging to assess blood flow around the hemorrhage at three different time points: immediately at the onset, after 24 hours, and after 7 days.
- Results showed that a significant portion of patients with initial oligemia (47.3%) progressed to ischemia by day 7, indicating that perihematomal oligemia is not as harmless as previously thought and is linked to poorer outcomes.
Acute-phase innate immune responses in SIVmac239-infected Indian rhesus macaques may contribute to the establishment of elite control.
Front Immunol
November 2024
Department of Immunology, Center for Innate Immunity and Immune Disease, School of Medicine, University of Washington, Seattle, WA, United States.
Article Synopsis
- The study investigates the spontaneous control of HIV/SIV viremia and its association with specific MHC class I allotypes, emphasizing the importance of CD8+ cytotoxic T lymphocytes (CTLs) for managing viral loads.
- Researchers aimed to understand the factors contributing to a phenotype known as elite controllers (ECs) by vaccinating rhesus macaques and analyzing immune responses after infection.
- Results showed that while vaccination did not prevent infection, it led to lower viral levels in vaccinated macaques, and 81% of them achieved elite control, highlighting differences in immune gene expression between vaccinated and unvaccinated groups.
Shock wave damage from the ventral side in primary blast injury: An experimental study in pigs.
Injury
December 2024
Department of Traumatology and Critical Care Medicine, NDMC, 3-2 Namiki, Tokorozawa, Saitama 359-8513, Japan.
Aim/purpose: This study aimed to apply a shock wave from the ventral side of a pig and examine its effect to use the results for new body armor production for humans.
Methods: Seven male hybrid pigs were used. Each pig was placed under general anesthesia on the experimental table in a blast tube in the left lateral position to expose the front chest area, and shock waves generated by compressed air at 3.
Hyperacute brain cyst after deep brain stimulation surgery: a case with complete spontaneous resolution.
Neurol Sci
October 2024
Diagnostic Neuroradiology Unit, Department of Radiology, Hospital Universitario Fundación Santa Fe de Bogotá, Carrera 7 #117-15, Bogotá, 110111, Colombia.
Spontaneous spinal epidural hematoma in children: a case report and literature review.
J Spine Surg
September 2024
Center for Minimally Invasive Spinal Surgery, Shin-Yurigaoka General Hospital, Kawasaki, Kanagawa, Japan.
Article Synopsis
- Spontaneous spinal epidural hematoma (SSEH) is a rare but serious condition in children that can lead to spinal cord compression and neurological issues, necessitating prompt diagnosis and intervention.
- A case study of a 14-year-old boy with SSEH showed successful treatment through emergent surgery, ultimately leading to complete recovery with no neurological deficits.
- Research identified 81 articles on SSEH in children, emphasizing the importance of early surgical intervention to alleviate pressure on the spinal cord and improve outcomes.
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