We show how to double copy heavy quark effective theory (HQET) to heavy black hole effective theory (HBET) for spin s≤1. In particular, the double copy of spin-s HQET with scalar QCD produces spin-s HBET, while the double copy of spin-1/2 HQET with itself gives spin-1 HBET. Finally, we present novel all-order-in-mass Lagrangians for spin-1 heavy particles.
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http://dx.doi.org/10.1103/PhysRevLett.125.181603 | DOI Listing |
Eur J Obstet Gynecol Reprod Biol
January 2025
Department of Clinical Laboratory, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, PR China. Electronic address:
Objective: To report a rare 17q12 microduplication family.
Case Report: A 29-year-old woman (gravida 1, para 0) underwent amniocentesis at 21 weeks' gestation because of double bubble sign and polyhydramnios of the fetus on prenatal ultrasound. Chromosomal microarray analysis (CMA) from this family revealed a 1.
Cell Genom
January 2025
Department of Genetics, Yale School of Medicine, New Haven, CT, USA. Electronic address:
Salivary and pancreatic amylase are encoded by AMY1 and AMY2, respectively, which are located within a single genomic locus that has undergone substantial structural variation, resulting in varying gene copy numbers across species. Using optical genome mapping and long-read sequencing, Yilmaz, Karageorgiou, Kim, et al. achieved nucleotide-level resolution of this locus across different human populations, offering new insights into how copy number variation contributes to human adaptation.
View Article and Find Full Text PDFNAR Genom Bioinform
March 2025
Department of Life Science and Medical Bioscience, Graduate School of Advanced Science and Engineering, Waseda University, 2-2 Wakamatsu-cho, Shinjuku-ku, Tokyo 162-8480, Japan.
Recent advancements in viral metagenomics and single-virus genomics have improved our ability to obtain the draft genomes of environmental viruses. However, these methods can introduce virus sequence contaminations into viral genomes when short, fragmented partial sequences are present in the assembled contigs. These contaminations can lead to incorrect analyses; however, practical detection tools are lacking.
View Article and Find Full Text PDFBiotechnol Biofuels Bioprod
January 2025
Department of Bioengineering, Imperial College Centre for Synthetic Biology, Bezos Centre for Sustainable Protein, UKRI Engineering Biology Mission Hub on Microbial Food, Imperial College London, London, SW7 2AZ, UK.
Background: Crocetin is a multifunctional apocarotenoid natural product derived from saffron, holding significant promises for protection against various diseases and other nutritional applications. Historically, crocetin has been extracted from saffron stigmas, but this method is hindered by the limited availability of high-quality raw materials and complex extraction processes. To overcome these challenges, metabolic engineering and synthetic biology can be applied to the sustainable production of crocetin.
View Article and Find Full Text PDFLINE-1 (L1) retrotransposition is widespread in many cancers, especially those with a high burden of chromosomal rearrangements. However, whether and to what degree L1 activity directly impacts genome integrity is unclear. Here, we apply whole-genome sequencing to experimental models of L1 expression to comprehensively define the spectrum of genomic changes caused by L1.
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