The cascading 3.21 and 4.44 MeV electric quadrupole transitions have been observed from the Hoyle state at 7.65 MeV excitation energy in ^{12}C, excited by the ^{12}C(p,p^{'}) reaction at 10.7 MeV proton energy. From the proton-γ-γ triple coincidence data, a value of Γ_{rad}/Γ=6.2(6)×10^{-4} was obtained for the radiative branching ratio. Using our results, together with Γ_{π}^{E0}/Γ from Eriksen et al. [Phys. Rev. C 102, 024320 (2020)PRVCAN2469-998510.1103/PhysRevC.102.024320] and the currently adopted Γ_{π}(E0) values, the radiative width of the Hoyle state is determined as Γ_{rad}=5.1(6)×10^{-3} eV. This value is about 34% higher than the currently adopted value and will impact models of stellar evolution and nucleosynthesis.
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http://dx.doi.org/10.1103/PhysRevLett.125.182701 | DOI Listing |
Chemosphere
February 2025
Wise Laboratory of Environmental and Genetic Toxicology, University of Louisville, Louisville, KY 40202, USA; Department of Pharmacology and Toxicology, University of Louisville, Louisville, KY 40202, USA. Electronic address:
Lung cancer is an important human health concern because of its high mortality rate, with many cases caused by environmental chemicals other than tobacco. Particulate hexavalent chromium [Cr(VI)] is a well-established human lung carcinogen, but how Cr(VI) induces lung cancer is poorly understood. Chromosome instability, a hallmark of lung cancer, is considered a major driving factor in Cr(VI)-induced lung cancer.
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December 2024
Department of Psychological Science, University of California, Irvine, Irvine, CA USA.
Unlabelled: Concerns regarding the potential negative impacts of digital technology use on youth mental health and well-being are high. However, most studies have several methodological limitations: relying on cross-sectional designs and retrospective reports, assessing technology use as an omnibus construct, and focusing on between- instead of within-person comparisons. This study addresses these limitations by prospectively following young adolescents ( = 388) over a 14-day ecological momentary assessment study to test whether adolescents' digital technology use is linked with self-reported emotional dysregulation and self-esteem and whether these relationships are stronger for adolescent girls than boys.
View Article and Find Full Text PDFSeismic imaging is one of the most powerful tools available for constraining the internal structure and composition of planetary bodies as well as enabling our understanding planetary evolution, geology, and distribution of natural resources. However, traditional seismic instrumentation can be heavy and voluminous, expensive, and/or difficult to rapidly deploy in large numbers. Distributed acoustic sensing (DAS) provides a promising new alternative given the ease of deployment, light weight and simplicity of fiber optic cables.
View Article and Find Full Text PDFSubst Use Misuse
January 2025
Department of Psychology and Neuroscience, Duke University, Durham, NC, USA.
Objective: Understanding factors associated with early onset of substance use is critical as using alcohol or drugs at a young age is a strong predictor of later substance dependency. Experiencing stressful life events is associated with increased risk for early substance use in youth. Hair cortisol concentration (HCC) is considered a biomarker of psychological stress experienced over longer periods of time.
View Article and Find Full Text PDFRSC Med Chem
September 2024
Department of Medicinal Chemistry, School of Pharmacy, Virginia Commonwealth University Richmond Virginia 23298-0540 USA
It has been demonstrated that the KDM3 family of histone demethylases (KDM3A and KDM3B) epigenetically control the functional properties of colorectal cancer stem cells (CSCs) through Wnt/β-catenin signaling. Meanwhile, a broad-spectrum histone demethylase inhibitor, IOX1, suppresses Wnt-induced colorectal tumorigenesis predominantly through inhibiting the enzymatic activity of KDM3. In this work, several cereblon (CRBN)-recruiting PROTACs with various linker lengths were designed and synthesized using IOX1 as a warhead to target KDM3 proteins for degradation.
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