Introduction: Algeria has more than 1.7 million diabetic patients on to whom a descriptive assessment particularly on the insulin usage behaviors has not yet been initiated, although is needed. This study aims to provide a descriptive analysis of how Algerian diabetic patients perceive and apply insulin injection techniques.
Methods: using the "patient" questionnaire within the Injection Technique Questionnaire (ITQ) 2016 survey, this study assessed the insulin injection practices of 100 patients recruited over a seven-month period in western Algeria at the Tlemcen University Hospital Center. The results of this study are compared to those of the ITQ 2016 survey.
Results: pens are the instruments of injection for 98% of Algerians who continue to use mostly long needles of 6- and 8-mm, although 4mm needles are the recommended safer option. Insulin analogues (fast and basal) are plebiscite. Arms and thighs are the preferred injection sites; the abdomen (the preferred site elsewhere) is neglected for reasons to be investigated. The correct re-suspension technique for cloudy insulin is unknown. Extensive pen needle re-use (10+ times) for over half of the patients exposes them to both higher intramuscular (IM) injection risk and lipohypertrophy (LH). Injection training is performed in Algeria by the diabetologist.
Conclusion: this study describes for the first time Algerian patients´ insulin injection technique. It highlights their skills and identifies many deficiencies which patients and professionals must correct given the issues in this area.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7603825 | PMC |
http://dx.doi.org/10.11604/pamj.2020.36.327.21278 | DOI Listing |
Alzheimers Dement
December 2024
Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
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View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Kentucky College of Medicine, Lexington, KY, USA.
Background: We have been investigating in vivo astrocytic Ca homeostasis in the primary somatosensory cortex (S1) of awake, head-restrained ambulating mice using two-photon technology. Prior results from our lab were obtained in neurons across aging, and in male and female C57Bl6/J mice (Case et al., 2023).
View Article and Find Full Text PDFAlzheimers Dement
December 2024
University of Kentucky College of Medicine, Lexington, KY, USA.
Background: We have recently published that overexpressing a constitutively active form of the insulin receptor beta subunit (IR-β) in hippocampal neurons ameliorates spatial memory performance in the F344 rat model of aging (Frazier et al., 2020). Because astrocytes express IRs and are central to cellular energy and information transfer in the brain, here we focus on the knockdown of IR in astrocytes of the primary somatosensory cortex (S1) in the 5xFAD animal model.
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View Article and Find Full Text PDFAlzheimers Dement
December 2024
Washington University in St. Louis School of Medicine, St. Louis, MO, USA.
Background: Obesity in midlife is a risk factor for developing Alzheimer disease later in life. However, the metabolic and inflammatory effects of body fat varies based on its anatomical localization. In this study, we aimed to investigate the association of MRI-derived abdominal visceral and subcutaneous adipose tissue (VAT and SAT), liver proton-density fat fraction (PDFF), thigh fat-to-muscle ratio (FMR), and insulin resistance with whole-brain amyloid burden in cognitively normal midlife individuals.
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