, also named Tianma, is a valuable traditional Chinese herbal medicine. It has numerous important pharmacological roles such as in sedation and lowering blood pressure and as anticonvulsant and anti-aging, and it also has effects on the immune and cardiovascular systems. The whole genome sequencing of has been completed in recent years, which provides a strong support for the construction of the gene functional analysis platform. Therefore, in our research, we collected and processed 39 transcriptome data of and constructed the gene co-expression networks, then we identified functional modules by the weighted correlation network analysis (WGCNA) package. Furthermore, gene families of were identified by tools including HMMER, iTAK, PfamScan, and InParanoid. Finally, we constructed a gene functional analysis platform for . In our platform, we introduced functional analysis tools such as BLAST, gene set enrichment analysis (GSEA), and elements (motif) enrichment analysis tool. In addition, we analyzed the co-expression relationship of genes which might participate in the biosynthesis of gastrodin and predicted 19 mannose-binding lectin antifungal proteins of . We also introduced the usage of the gene function analysis platform (GelFAP) by analyzing and genes. Our platform GelFAP may help researchers to explore the gene function of and make novel discoveries about key genes involved in the biological processes of gastrodin.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7642037PMC
http://dx.doi.org/10.3389/fpls.2020.563237DOI Listing

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