Robotic exoskeletons are developed with the aim of enhancing convenience and physical possibilities in daily life. However, at present, these devices lack sufficient synchronization with human movements. To optimize human-exoskeleton interaction, this article proposes a gait recognition and prediction model, called the gait neural network (GNN), which is based on the temporal convolutional network. It consists of an intermediate network, a target network, and a recognition and prediction model. The novel structure of the algorithm can make full use of the historical information from sensors. The performance of the GNN is evaluated based on the publicly available HuGaDB dataset, as well as on data collected by an inertial-based wearable motion capture device. The results show that the proposed approach is highly effective and achieves superior performance compared with existing methods.
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http://dx.doi.org/10.3389/fnbot.2020.00058 | DOI Listing |
Sci Rep
January 2025
Department of Dermatology, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, 710061, China.
Brodalumab, a humanized monoclonal antibody that targets the interleukin-17 receptor A, is primarily used to manage moderate-to-severe plaque psoriasis. Although it has demonstrated favorable efficacy and safety in clinical trials, the strict inclusion and exclusion criteria may not fully reflect its safety profile in real-world settings. As its use becomes more widespread in clinical practice, understanding its safety in real-world applications is crucial.
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January 2025
Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.
The current gold standard for the study of human movement is the marker-based motion capture system that offers high precision but constrained by costs and controlled environments. Markerless pose estimation systems emerge as ecological alternatives, allowing unobtrusive data acquisition in natural settings. This study compares the performance of two popular markerless systems, OpenPose (OP) and DeepLabCut (DLC), in assessing locomotion.
View Article and Find Full Text PDFCommun Med (Lond)
January 2025
Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, USA.
Background: Declining gait performance is seen in aging individuals, due to neural and systemic factors. Plasma biomarkers provide an accessible way to assess evolving brain changes; non-specific neurodegeneration (NfL, GFAP) or evolving Alzheimer's disease (Aβ 42/40 ratio, P-Tau181).
Methods: In a population-based cohort of older adults, we evaluate the hypothesis that plasma biomarkers of neurodegeneration and Alzheimer's Disease pathology are associated with worse gait performance.
Appl Sci (Basel)
June 2024
Department of Biomechanics and Center for Research in Human Movement Variability, University of Nebraska at Omaha, Omaha, NE 68182, USA.
Understanding metabolic cost through biomechanical data, including ground reaction forces (GRFs) and joint moments, is vital for health, sports, and rehabilitation. The long stabilization time (2-5 min) of indirect calorimetry poses challenges in prolonged tests. This study investigated using artificial neural networks (ANNs) to predict metabolic costs from the GRF and joint moment time series.
View Article and Find Full Text PDFWearable Technol
December 2024
Biorobotics Laboratory, EPFL, Lausanne, Vaud, Switzerland.
Neuromuscular controllers (NMCs) offer a promising approach to adaptive and task-invariant control of exoskeletons for walking assistance, leveraging the bioinspired models based on the peripheral nervous system. This article expands on our previous development of a novel structure for NMCs with modifications to the virtual muscle model and reflex modulation strategy. The modifications consist firstly of simplifications to the Hill-type virtual muscle model, resulting in a more straightforward formulation and reduced number of parameters; and second, using a finer division of gait subphases in the reflex modulation state machine, allowing for a higher degree of control over the shape of the assistive profile.
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