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[Pediatric reference values for alkaline phosphatase and pathophysiological variations]. | LitMetric

[Pediatric reference values for alkaline phosphatase and pathophysiological variations].

Ann Biol Clin (Paris)

Laboratoire de biochimie-pharmacologie-toxicologie, Pôle de biologie territoriale, CHU Reims, France.

Published: December 2020

Alkaline phosphatase activity is a parameter included in biochemical liver test. These isoenzymes are of various cellular origin inducing physiological variations on age and sex. The alkaline phosphatase activity standardization as well as numerous international studies have made it possible to standardize the pediatric reference values. The hyperphosphatasemia etiologies are very well know but the hypophosphatasemia are hardly explored and can allow the diagnosis of pathologies including hypophosphatasia, a rare treatable disease.

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Source
http://dx.doi.org/10.1684/abc.2020.1598DOI Listing

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